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Basic Information | |
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Species | Vitis vinifera |
Cazyme ID | GSVIVT01001143001 |
Family | GT47 |
Protein Properties | Length: 450 Molecular Weight: 52123.7 Isoelectric Point: 9.5991 |
Chromosome | Chromosome/Scaffold: 1 Start: 22983271 End: 23001188 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 116 | 400 | 0 |
KLKIFVYPDASMNQSSSPFARVFLPNPNPFHPKLANYFSEHMFKVALLRSSLLTPHPQDAHFFFLPFSVNTLRNDPRVHSEASISDFVTQYTTRISWEYK FWNASRGTDHFYICCHSVGREAASKHHDLHNNAIQVTCSSSYFQRLYISHKDVGLPQVWPRPPEKLLNPPELRHKLVFFAGRVQNSHIRQELMAVWGNDT DIDLFSGSPPFPYEEGLRKSKYCLHVKGYEVNTARVCDAIHYGCIPVIVSNYYDLPFSNVLDWSKFSVIISHKSIATLKKILLSI |
Full Sequence |
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Protein Sequence Length: 450 Download |
MRRPHTCFSE KPQQHLILPH RRLLLVRPPL LLVLLLLLTL TVSSWLAVFL CGFSKPRQQQ 60 VPSLEFNESL NNNNAHHSSA ESVQDRNDSL SSGNLLGSPY HNWQLFASDF QEMLHKLKIF 120 VYPDASMNQS SSPFARVFLP NPNPFHPKLA NYFSEHMFKV ALLRSSLLTP HPQDAHFFFL 180 PFSVNTLRND PRVHSEASIS DFVTQYTTRI SWEYKFWNAS RGTDHFYICC HSVGREAASK 240 HHDLHNNAIQ VTCSSSYFQR LYISHKDVGL PQVWPRPPEK LLNPPELRHK LVFFAGRVQN 300 SHIRQELMAV WGNDTDIDLF SGSPPFPYEE GLRKSKYCLH VKGYEVNTAR VCDAIHYGCI 360 PVIVSNYYDL PFSNVLDWSK FSVIISHKSI ATLKKILLSI SKQKYLSMYQ NLCLVRRHFA 420 WHTTPRGYDS FHMTAYQLWL RRGVHRLSY* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-44 | 113 | 387 | 292 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI29307.1 | 0 | 1 | 449 | 1 | 449 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 100 | 447 | 105 | 443 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268876.1 | 0 | 283 | 449 | 17 | 183 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002297901.1 | 0 | 95 | 449 | 92 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512716.1 | 0 | 91 | 449 | 64 | 426 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |