| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01001277001 |
| Family | GT47 |
| Protein Properties | Length: 294 Molecular Weight: 33988.5 Isoelectric Point: 5.7602 |
| Chromosome | Chromosome/Scaffold: 2 Start: 4921780 End: 4923609 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 48 | 286 | 1.3e-34 |
| CTNRWIHIRRLPTRFNLDLLTNCSEYPVFDDFCPYLANHGLGQKTHNNSHSWYRTDPLILELVFHRRMLEYPCLTSDPSAADAIFLPYYGGIDAIRYLFG PEVNSSFEHGLELYEFLQQDSPEVWSRNGGHNHFTVLARPAWDFSQSLDNDPPIWGTSFLELPEFYNITVLTLESRPWPWQEQAIPYPTSFHPASLVLLD SWVQRVRRSRRTTLMLFAGGGGTSLLPNIRRSIRSECDN | |||
| Full Sequence |
|---|
| Protein Sequence Length: 294 Download |
| MVGQTFPQMT SGFFSMASRP RILIWVAFFF FFEFVFCESV IDPDAPECTN RWIHIRRLPT 60 RFNLDLLTNC SEYPVFDDFC PYLANHGLGQ KTHNNSHSWY RTDPLILELV FHRRMLEYPC 120 LTSDPSAADA IFLPYYGGID AIRYLFGPEV NSSFEHGLEL YEFLQQDSPE VWSRNGGHNH 180 FTVLARPAWD FSQSLDNDPP IWGTSFLELP EFYNITVLTL ESRPWPWQEQ AIPYPTSFHP 240 ASLVLLDSWV QRVRRSRRTT LMLFAGGGGT SLLPNIRRSI RSECDNTLPH FTV* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-26 | 92 | 287 | 207 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI25781.1 | 0 | 13 | 293 | 49 | 329 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI31889.1 | 0 | 1 | 293 | 1 | 293 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002267390.1 | 0 | 16 | 287 | 1 | 272 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002304426.1 | 0 | 47 | 287 | 28 | 268 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002529790.1 | 0 | 21 | 287 | 4 | 276 | catalytic, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2dxq_B | 0.009 | 158 | 232 | 20 | 88 | A Chain A, Putative Acetyltransferase From Agrobacterium Tumefaciens Str. C58 |
| PDB | 2dxq_A | 0.009 | 158 | 232 | 20 | 88 | A Chain A, Putative Acetyltransferase From Agrobacterium Tumefaciens Str. C58 |
