| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01004778001 |
| Family | GT47 |
| Protein Properties | Length: 330 Molecular Weight: 38337.6 Isoelectric Point: 5.0829 |
| Chromosome | Chromosome/Scaffold: Start: 16036957 End: 16042128 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 84 | 322 | 3e-35 |
| CTNRWIHIRRLPTRFNLDLLTNCSEYPVFDDFCPYLANHGLGQKTHNNSHSWYRTDPLMLELVFHRRMLEYPCLTSDPSAADAIFLPYYGGIDAIRYLFG PEVNSSFEHGLELYEFLQQDSPEVWSRNGGHDHFTVLARPAWDFSQSLDNDPPIWGTSFLELPEFYNITVLTLESRPWPWQEQAIPYPTSFHPVSLVLLD SWVQRVRRSRRTTLMLFAGGGGTSLLPNIRRSIRSECEN | |||
| Full Sequence |
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| Protein Sequence Length: 330 Download |
| MKGIKLRLEV LEECEKKTKG EEEENCTFLF PQSSYSLFFI SLPLNPDFLF SMASRPRILI 60 WVAFFFFFEF VFCESVVDPD APECTNRWIH IRRLPTRFNL DLLTNCSEYP VFDDFCPYLA 120 NHGLGQKTHN NSHSWYRTDP LMLELVFHRR MLEYPCLTSD PSAADAIFLP YYGGIDAIRY 180 LFGPEVNSSF EHGLELYEFL QQDSPEVWSR NGGHDHFTVL ARPAWDFSQS LDNDPPIWGT 240 SFLELPEFYN ITVLTLESRP WPWQEQAIPY PTSFHPVSLV LLDSWVQRVR RSRRTTLMLF 300 AGGGGTSLLP NIRRSIRSEC ENTLSHFTV* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-27 | 128 | 323 | 207 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI25781.1 | 0 | 1 | 329 | 1 | 329 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI31889.1 | 0 | 50 | 329 | 14 | 293 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002267390.1 | 0 | 52 | 323 | 1 | 272 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002304426.1 | 0 | 83 | 323 | 28 | 268 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002529790.1 | 0 | 57 | 323 | 4 | 276 | catalytic, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2dxq_B | 0.01 | 194 | 268 | 20 | 88 | A Chain A, Putative Acetyltransferase From Agrobacterium Tumefaciens Str. C58 |
| PDB | 2dxq_A | 0.01 | 194 | 268 | 20 | 88 | A Chain A, Putative Acetyltransferase From Agrobacterium Tumefaciens Str. C58 |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FQ427139 | 241 | 25 | 265 | 0 |
| FQ429409 | 232 | 25 | 256 | 0 |
| FQ424787 | 226 | 25 | 250 | 0 |
| FQ432794 | 222 | 25 | 246 | 0 |
| FQ444368 | 214 | 25 | 238 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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