Basic Information | |
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Species | Vitis vinifera |
Cazyme ID | GSVIVT01006274001 |
Family | GT47 |
Protein Properties | Length: 586 Molecular Weight: 67380.3 Isoelectric Point: 10.0296 |
Chromosome | Chromosome/Scaffold: Start: 24409833 End: 24415551 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 203 | 487 | 0 |
LKVYIYPDGARPIFHAPHLRGIYASEGWFMKLMEENRQFVTRDPKKAHLFYLPYSARQLETALYVPNSHNIRPLSIFLRDHVNMIAAKYPFWNRTHGSDH FLVACHDWGPYTVNEHQELSRNTIKALCNADLSEGIFVAGKDVSLPETTIRNPRRPLRNVGGRRVSQRPILAFFAGNMHGRVRPTLLKYWSDKDEDMRIY GPLPNRISRKMSYIQHMKSSRFCICPMGYEVNSPRIVEAIYYECVPVIIADNFVPPLNDVLDWTAFSVIVAEKDIPKLKEILLAI |
Full Sequence |
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Protein Sequence Length: 586 Download |
MKRLLQLVAV VLMYRINWKK LFVVVAIMTT AGMVLQTYTL PYPMATWFLP PQTMVSSYKS 60 LNGSTVHLTE TLSLESAEQF QLVPTAPVVS LNSSTELVKS VPIVEERAQV SPRRNPSSRR 120 RRKNAKIDKT NEQKVVFHPP PPRTVPTRLQ RYIWSLPPDE ALLFAKREIQ NVSTVTDDPE 180 LYASLFHNVS VFKRSYELME TILKVYIYPD GARPIFHAPH LRGIYASEGW FMKLMEENRQ 240 FVTRDPKKAH LFYLPYSARQ LETALYVPNS HNIRPLSIFL RDHVNMIAAK YPFWNRTHGS 300 DHFLVACHDW GPYTVNEHQE LSRNTIKALC NADLSEGIFV AGKDVSLPET TIRNPRRPLR 360 NVGGRRVSQR PILAFFAGNM HGRVRPTLLK YWSDKDEDMR IYGPLPNRIS RKMSYIQHMK 420 SSRFCICPMG YEVNSPRIVE AIYYECVPVI IADNFVPPLN DVLDWTAFSV IVAEKDIPKL 480 KEILLAIPLR RYLVMQTNVK MVQKHFLWNP KPVRYDLFHM ILHSIWFSRL NQIQISVNDT 540 APVALGLRLI IRKSSCIKLK TGIISSDGSN GDGQNEDFTT QEDSV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-68 | 203 | 487 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 1 | 585 | 1 | 585 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 15 | 542 | 27 | 540 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 1 | 538 | 1 | 538 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303362.1 | 0 | 154 | 535 | 1 | 383 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530666.1 | 0 | 11 | 535 | 9 | 525 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |