| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01010019001 |
| Family | GT47 |
| Protein Properties | Length: 460 Molecular Weight: 52690.6 Isoelectric Point: 9.6663 |
| Chromosome | Chromosome/Scaffold: 18 Start: 13498401 End: 13504533 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT47 | 85 | 382 | 0 |
| SLKIYVYEEDEIDGLKSLLYGRDGSIPTEVCVTGQWGTQVKIHRLLLKSRFRTRRKEEADLFFVPTYIKCVRMKGGLNDKEIDQMYVKVLSQMPYFRLSG GRNHIFVFPSGAGPHLFKSWATYLNRSIILTPEGDRTDKKDTSAFNTWKDIIIPGNVADEMTTNGATFVQPLPLSKRKFLANFLGRAQRKLGRLQLIELA KQYPDKLESPELQFSGPDKLGRIEYFHHLRNAKFCFAPRGESSWTLRFYESFFVECVPVILSDQVELPFQNVIDYTQVSIKWPSSQIGPQLLEYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 460 Download |
| MGSPNNKHRA FTSHTHHGLC TRTHQIAALA LIIVTFFLTR LLDRSFSPCA SQASVAQLPG 60 SRTVLRVNGG GSLSWPERGY GSQLSLKIYV YEEDEIDGLK SLLYGRDGSI PTEVCVTGQW 120 GTQVKIHRLL LKSRFRTRRK EEADLFFVPT YIKCVRMKGG LNDKEIDQMY VKVLSQMPYF 180 RLSGGRNHIF VFPSGAGPHL FKSWATYLNR SIILTPEGDR TDKKDTSAFN TWKDIIIPGN 240 VADEMTTNGA TFVQPLPLSK RKFLANFLGR AQRKLGRLQL IELAKQYPDK LESPELQFSG 300 PDKLGRIEYF HHLRNAKFCF APRGESSWTL RFYESFFVEC VPVILSDQVE LPFQNVIDYT 360 QVSIKWPSSQ IGPQLLEYLE SIPDKVIEEM ISRGREVRCW WVYASESEPC SAMRGIMWEL 420 QRKVRKFHQS TETFWLHNGS IINRNLEQFS NWKPPMPLP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-42 | 86 | 382 | 311 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564141.1 | 0 | 5 | 459 | 6 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 1 | 459 | 1 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 1 | 459 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 1 | 459 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 5 | 459 | 9 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX668832 | 291 | 146 | 436 | 0 |
| FE707914 | 279 | 126 | 404 | 0 |
| FE707913 | 274 | 187 | 460 | 0 |
| EH692645 | 270 | 163 | 432 | 0 |
| HO781282 | 326 | 19 | 343 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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