| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01010454001 |
| Family | GT47 |
| Protein Properties | Length: 442 Molecular Weight: 51367.9 Isoelectric Point: 8.2319 |
| Chromosome | Chromosome/Scaffold: 1 Start: 20746045 End: 20750153 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 1 | 376 | 0 |
| MYDLPRRFHVGMLRRRSPADESPVTAENLPPWPSNSGLKKQHSVEYWMMASLLYDGGGGNETREAVRVWDPEMADAFFVPFFSSLSFNTHGHNMTDPDTE FDRQLQIDILKILRESKYWQRSGGRDHVIPMHHPNAFRFFREQVNTSILIVADFGRYPKEISNLRKDVVAPYVHVVDSFTDDNSPDPYESRTTLLFFRGR TIRKDEGIVRDKLVKLLAGHTLHVIHVLAACTLPLSFAESSIFEGSVMAVYYIVVGWCLRCRSKKISIVELWQSKELIIQVVKAAGFLSKLCSCQLWGVH STQGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDQIELPYEDEIDYTQFSIFFSDKEALEPGYMIEQLRQI | |||
| Full Sequence |
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| Protein Sequence Length: 442 Download |
| MYDLPRRFHV GMLRRRSPAD ESPVTAENLP PWPSNSGLKK QHSVEYWMMA SLLYDGGGGN 60 ETREAVRVWD PEMADAFFVP FFSSLSFNTH GHNMTDPDTE FDRQLQIDIL KILRESKYWQ 120 RSGGRDHVIP MHHPNAFRFF REQVNTSILI VADFGRYPKE ISNLRKDVVA PYVHVVDSFT 180 DDNSPDPYES RTTLLFFRGR TIRKDEGIVR DKLVKLLAGH TLHVIHVLAA CTLPLSFAES 240 SIFEGSVMAV YYIVVGWCLR CRSKKISIVE LWQSKELIIQ VVKAAGFLSK LCSCQLWGVH 300 STQGMRSSKF CLHPAGDTPS SCRLFDAIVS HCVPVIVSDQ IELPYEDEID YTQFSIFFSD 360 KEALEPGYMI EQLRQIPKER WVEMWRHLKY ISHHYEFQYP PKKGDAIDML WRQVKHKLPR 420 ANLDVHRSRR LKVPDWWDHR R* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-24 | 301 | 376 | 76 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 9.0e-30 | 1 | 227 | 235 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC18793.1 | 0 | 1 | 418 | 57 | 440 | End is cut off [Arabidopsis thaliana] |
| GenBank | ABK24530.1 | 0 | 1 | 440 | 70 | 446 | unknown [Picea sitchensis] |
| EMBL | CBI27633.1 | 0 | 1 | 441 | 1 | 441 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002272591.1 | 0 | 1 | 218 | 57 | 274 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002272591.1 | 0 | 281 | 441 | 264 | 430 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EC955869 | 344 | 72 | 415 | 0 |
| CO083280 | 219 | 1 | 219 | 0 |
| FC914943 | 220 | 1 | 220 | 0 |
| FC882560 | 220 | 1 | 220 | 0 |
| DY282008 | 220 | 1 | 220 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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