Basic Information | |
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Species | Vitis vinifera |
Cazyme ID | GSVIVT01012106001 |
Family | GT47 |
Protein Properties | Length: 462 Molecular Weight: 52794.4 Isoelectric Point: 7.4936 |
Chromosome | Chromosome/Scaffold: 1 Start: 1418372 End: 1422376 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 72 | 385 | 0 |
VKVYMYDLPRKFTYGVIESYAVARGGLEKVPVDDVSSLKYPGHQHSGEWYLFSDLIREDRGRRYVVRVSDPEEADLFYVSFFSSLSLVVNPIRPANGEGA GTGYSDEEMQESLMEWLEQQEYWKRNNGRDHVFICQDPNALHLIVDRVKNGVLLVSDFGRLRSDTASLVKDVILPYAHRIKSYSGEIGVENRKSLLFFMG NRYRKEGGKIRDLLFQILEQEEDVIIKHGAQSRESRRMASQGMHSSKFCLHPAGDTPSACRLFDAIVSLCVPVIVSDQIELPFEDVIDYRKIAIFVDSTS AVKPGFLVKNLRKI |
Full Sequence |
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Protein Sequence Length: 462 Download |
MARKSILKST VVTVLCVFGL YGLSTTFFNP INPYHSRLDL SLPLDSSSKS LSLLSTDSGE 60 NLSKFSRNFG PVKVYMYDLP RKFTYGVIES YAVARGGLEK VPVDDVSSLK YPGHQHSGEW 120 YLFSDLIRED RGRRYVVRVS DPEEADLFYV SFFSSLSLVV NPIRPANGEG AGTGYSDEEM 180 QESLMEWLEQ QEYWKRNNGR DHVFICQDPN ALHLIVDRVK NGVLLVSDFG RLRSDTASLV 240 KDVILPYAHR IKSYSGEIGV ENRKSLLFFM GNRYRKEGGK IRDLLFQILE QEEDVIIKHG 300 AQSRESRRMA SQGMHSSKFC LHPAGDTPSA CRLFDAIVSL CVPVIVSDQI ELPFEDVIDY 360 RKIAIFVDST SAVKPGFLVK NLRKITRERI LEYQREMQEV TRYFEYEDTN GTVSEIWRQV 420 SMKLPLIKLM INRDKRLVKR EMTEPDCSCL CSNQSEIRTF L* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-65 | 71 | 385 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68074.1 | 0 | 1 | 461 | 1 | 461 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_850241.1 | 0 | 72 | 459 | 60 | 445 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002276440.1 | 0 | 1 | 461 | 34 | 494 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002322391.1 | 0 | 1 | 455 | 1 | 451 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 1 | 455 | 1 | 446 | catalytic, putative [Ricinus communis] |