| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01012525001 |
| Family | GT47 |
| Protein Properties | Length: 327 Molecular Weight: 38206 Isoelectric Point: 9.4619 |
| Chromosome | Chromosome/Scaffold: 3 Start: 594622 End: 613113 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 4 | 279 | 0 |
| KFKVFVYPDGDPNTYYQTPRKLTGKYASEGYFFQNIRQSQFRTDDPDQAHLFFIPISCHKMRGKGTSYENMTIIVQNYVQSLMSKYPYWNRTLGADHFFL TCHDVGVRATEGVPLLVKNSIRVVCSPSYDVGFIPHKDVALPQVLQPFALPTGGRDIKNRTTLGFWAGHRNSKIRVILARIWENDTELDIKNNRINRATG HLVYQNKFYRTKFCICPGGSQVNSARIADSIHYGCVPVILSDYYDLPFNDILDWRKFSVILKERDVYRLKYILKDI | |||
| Full Sequence |
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| Protein Sequence Length: 327 Download |
| MEMKFKVFVY PDGDPNTYYQ TPRKLTGKYA SEGYFFQNIR QSQFRTDDPD QAHLFFIPIS 60 CHKMRGKGTS YENMTIIVQN YVQSLMSKYP YWNRTLGADH FFLTCHDVGV RATEGVPLLV 120 KNSIRVVCSP SYDVGFIPHK DVALPQVLQP FALPTGGRDI KNRTTLGFWA GHRNSKIRVI 180 LARIWENDTE LDIKNNRINR ATGHLVYQNK FYRTKFCICP GGSQVNSARI ADSIHYGCVP 240 VILSDYYDLP FNDILDWRKF SVILKERDVY RLKYILKDIP DAEFIALHDN LVKVQKHFQW 300 NTPPIKYDAF HMVMYELWLR HHVIKY* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-55 | 4 | 279 | 297 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI38234.1 | 0 | 1 | 326 | 1 | 326 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002266299.1 | 0 | 1 | 326 | 91 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268836.1 | 0 | 1 | 326 | 92 | 417 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002307304.1 | 0 | 1 | 326 | 81 | 406 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002522880.1 | 0 | 1 | 326 | 81 | 406 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EH770778 | 275 | 17 | 291 | 0 |
| GO268625 | 269 | 1 | 269 | 0 |
| EX317869 | 278 | 26 | 303 | 0 |
| EG459159 | 264 | 64 | 327 | 0 |
| EE617569 | 250 | 4 | 253 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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