| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01012711001 |
| Family | CBM43 |
| Protein Properties | Length: 962 Molecular Weight: 105728 Isoelectric Point: 6.8492 |
| Chromosome | Chromosome/Scaffold: 10 Start: 876735 End: 883328 |
| Description | O-Glycosyl hydrolases family 17 protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CBM43 | 385 | 466 | 2.4e-33 |
| CIAMDGVDARTLQAALDWACGPGRANCSEIQPGEGCYQPNNVKNHASYAFDSYYQKEGRGSGSCDFKGVAMITTTDPSHGSC | |||
| GH17 | 47 | 366 | 0 |
| VGVNIGTDVSNLLSPADLVAFLKLQNIGHVRLYDADSDILKALARTKIRVIVSVPNNQLLAIGSSNVTAATWIGRNVVAYYPETLITAIAVGDEVLTTVS SSAPLLLPAIEALYSALVAANLHTEIKISTPHAASIILDPFPPSQAFFNQTLNPIILPLLQFLSKTGSPLMMNLYPYYVFMQNKGVVPLDNSLFKPLTPS KEMVDPNTLLHYTNVLDAMIDSVYCSMKNLNVTDVMVLVTESGWPSRGDSKEPYATIDNADTYNSNLIKHVLDHSGSPLHPELTSSVYIYELFNEDLRSP PVSEANWGLFHGNSTPVYLL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 962 Download |
| MKKWSSSFSS MADSKRFLLV FLICTVLSES GIVAEVKQTQ GRAEPFVGVN IGTDVSNLLS 60 PADLVAFLKL QNIGHVRLYD ADSDILKALA RTKIRVIVSV PNNQLLAIGS SNVTAATWIG 120 RNVVAYYPET LITAIAVGDE VLTTVSSSAP LLLPAIEALY SALVAANLHT EIKISTPHAA 180 SIILDPFPPS QAFFNQTLNP IILPLLQFLS KTGSPLMMNL YPYYVFMQNK GVVPLDNSLF 240 KPLTPSKEMV DPNTLLHYTN VLDAMIDSVY CSMKNLNVTD VMVLVTESGW PSRGDSKEPY 300 ATIDNADTYN SNLIKHVLDH SGSPLHPELT SSVYIYELFN EDLRSPPVSE ANWGLFHGNS 360 TPVYLLHVSG SGTFLANDTT NQTFCIAMDG VDARTLQAAL DWACGPGRAN CSEIQPGEGC 420 YQPNNVKNHA SYAFDSYYQK EGRGSGSCDF KGVAMITTTD PSHGSCIFPG SKKISNKTKE 480 AINGTEASGA AVQLRLVTVG SQINKDPISA QCFKMALSHV LRSSPFRFLC RINPRKTLHF 540 QFKPMSWTCS KCTFINPSSQ TSTCLICSSS SSIPQSPSSS SAPSPSTPKW SCKACTFLNP 600 YRNPICEVCG TRASVSSLSC FEDLNCTDPD GELDSSVGSV FLPLQRCSKR KNRDPVEIDA 660 AAGGSGGFGG VKSANKAVVA LEDTDSDSVL SSLKILSYNV WFREDLEMDK RMQALGDLIQ 720 LHSPDLICFQ EVTPNIYDVF QQSCWWKVYR CSVPNEMAHL RPYFCMLLSK LPVKSFSCKR 780 FSNSIMGREL CIAELEVQAG KPLVLATSHL ESPCPAPPKW DQMYSKERVD QAKEALNLLT 840 KNPNVIFGGD MNWDEKSDGQ FPLPDGWVDA WADLRPGENG WTYDTKSNQM LSGNRTLQKR 900 LDRFMCRLHD FKISKIDMIG MEPIPGLSYC KEKKVRKEMQ QLVLPVLPSD HYGLLLTISS 960 Q* 1020 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd08372 | EEP | 2.0e-9 | 695 | 958 | 288 | + Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily. This large superfamily includes the catalytic domain (exonuclease/endonuclease/phosphatase or EEP domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds; their substrates range from nucleic acids to phospholipids and perhaps proteins. | ||
| pfam07983 | X8 | 2.0e-22 | 383 | 455 | 78 | + X8 domain. The X8 domain domain contains at least 6 conserved cysteine residues that presumably form three disulphide bridges. The domain is found in an Olive pollen allergen as well as at the C-terminus of several families of glycosyl hydrolases. This domain may be involved in carbohydrate binding. This domain is characteristic of GPI-anchored domains. | ||
| smart00768 | X8 | 2.0e-40 | 383 | 468 | 86 | + Possibly involved in carbohydrate binding. The X8 domain, which may be involved in carbohydrate binding, is found in an Olive pollen antigen as well as at the C terminus of family 17 glycosyl hydrolases. It contains 6 conserved cysteine residues which presumably form three disulfide bridges. | ||
| cd09080 | TDP2 | 2.0e-81 | 693 | 958 | 272 | + Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains. Human TDP2, also known as TTRAP (TRAF/TNFR-associated factors, and tumor necrosis factor receptor/TNFR-associated protein), is a 5'-tyrosyl DNA phosphodiesterase. It is required for the efficient repair of topoisomerase II-induced DNA double strand breaks. The topoisomerase is covalently linked by a phosphotyrosyl bond to the 5'-terminus of the break. TDP2 cleaves the DNA 5'-phosphodiester bond and restores 5'-phosphate termini, needed for subsequent DNA ligation, and hence repair of the break. TDP2 and 3'-tyrosyl DNA phosphodiesterase (TDP1) are complementary activities; together, they allow cells to remove trapped topoisomerase from both 3'- and 5'-DNA termini. TTRAP has been reported as being involved in apoptosis, embryonic development, and transcriptional regulation, and it may inhibit the activation of nuclear factor-kB. This family belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. | ||
| pfam00332 | Glyco_hydro_17 | 2.0e-84 | 47 | 364 | 318 | + Glycosyl hydrolases family 17. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005622 | intracellular |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008270 | zinc ion binding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI23232.1 | 0 | 1 | 961 | 1 | 961 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002268030.1 | 0 | 545 | 961 | 1 | 413 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002316541.1 | 0 | 59 | 526 | 1 | 469 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002332610.1 | 0 | 59 | 501 | 1 | 443 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002518468.1 | 0 | 11 | 501 | 1 | 504 | Glucan endo-1,3-beta-glucosidase precursor, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2cyg_A | 0 | 47 | 364 | 1 | 308 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
| PDB | 3ur8_B | 0 | 47 | 369 | 3 | 315 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
| PDB | 3ur8_A | 0 | 47 | 369 | 3 | 315 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
| PDB | 3ur7_B | 0 | 47 | 369 | 3 | 315 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
| PDB | 3ur7_A | 0 | 47 | 369 | 3 | 315 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
