| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01012805001 |
| Family | GT47 |
| Protein Properties | Length: 276 Molecular Weight: 32143.8 Isoelectric Point: 9.5487 |
| Chromosome | Chromosome/Scaffold: 11 Start: 5550176 End: 5552396 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 56 | 213 | 3.8e-40 |
| EKRFKIWTYKEGDQPLVHGGPKNSIYGIEGQFMDEMESGDSHFVAGHPDEAHVFYIPISVTRIAHYIYSPPVDYSGHMLQRLVTDYIYVVSDKYPYWNRS NGADHFLVSCHDWAPEISIVTPDLYKHFIRVLCNANTSERFQPIRDISLPEFSINITS | |||
| Full Sequence |
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| Protein Sequence Length: 276 Download |
| MSPLERIEGG LASARAAIRE AVRSSNYTSQ KKENFIPRGA VYRNPYAFHQ SHIEMEKRFK 60 IWTYKEGDQP LVHGGPKNSI YGIEGQFMDE MESGDSHFVA GHPDEAHVFY IPISVTRIAH 120 YIYSPPVDYS GHMLQRLVTD YIYVVSDKYP YWNRSNGADH FLVSCHDWAP EISIVTPDLY 180 KHFIRVLCNA NTSERFQPIR DISLPEFSIN ITSDKIPEIK KILKAVPNER YLRMQKRVKQ 240 VQRHFVINRP AQPYDMLHMI LHSVWLRRLN VRLRS* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-21 | 55 | 230 | 185 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI25527.1 | 0 | 1 | 275 | 1 | 275 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI25529.1 | 0 | 1 | 232 | 1 | 228 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI25529.1 | 2e-36 | 206 | 275 | 319 | 388 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002264922.1 | 0 | 55 | 232 | 1 | 174 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002264922.1 | 1e-36 | 206 | 275 | 265 | 334 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| JG591774 | 208 | 2 | 209 | 0 |
| EC939466 | 213 | 2 | 209 | 0 |
| GO543398 | 185 | 16 | 200 | 0 |
| ES268549 | 167 | 6 | 172 | 0 |
| EL439451 | 215 | 4 | 217 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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