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Basic Information | |
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Species | Vitis vinifera |
Cazyme ID | GSVIVT01012808001 |
Family | GT47 |
Protein Properties | Length: 388 Molecular Weight: 45317 Isoelectric Point: 9.1273 |
Chromosome | Chromosome/Scaffold: 11 Start: 5586712 End: 5591626 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 56 | 338 | 0 |
EKRFKIWAYREGDQPLMHDGPSNDIYAIEGQFMDEIESGKSQFLARHPDEANAFYIPMSLTRVVHFIYEPPHYHGKWIPRLVTDYINFVADKYPYWNRSK GADHFLVSCHDWAPDVSALKPDLYKHFIRALCNANTSERFHPIRDISIPEINIPRGKLGPPHLDQPPNKRPILAFFAGGAHGYVRSVLFKYWKEKDDEVQ VFERLPRNRNYSKSMGDSKFCLCPSGYEVASPRIVEAIAAGCVPMIICDHYSLPFSDVLDWSKFSIYITSDKIPEIKKILKAV |
Full Sequence |
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Protein Sequence Length: 388 Download |
MSHVERIEEG LARAREAIRR AIQRRNYSSE KEETFIPRGD VYRNPYAFHQ SHIEMEKRFK 60 IWAYREGDQP LMHDGPSNDI YAIEGQFMDE IESGKSQFLA RHPDEANAFY IPMSLTRVVH 120 FIYEPPHYHG KWIPRLVTDY INFVADKYPY WNRSKGADHF LVSCHDWAPD VSALKPDLYK 180 HFIRALCNAN TSERFHPIRD ISIPEINIPR GKLGPPHLDQ PPNKRPILAF FAGGAHGYVR 240 SVLFKYWKEK DDEVQVFERL PRNRNYSKSM GDSKFCLCPS GYEVASPRIV EAIAAGCVPM 300 IICDHYSLPF SDVLDWSKFS IYITSDKIPE IKKILKAVPT ETYLEMQKRV KQVQRHFAIN 360 RPARPYDMLH MILHSVWLRR LNVRLPS* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-62 | 55 | 338 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN73458.1 | 0 | 55 | 387 | 1 | 333 | hypothetical protein [Vitis vinifera] |
EMBL | CBI25528.1 | 0 | 25 | 387 | 500 | 862 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25529.1 | 0 | 1 | 387 | 1 | 388 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002266490.1 | 0 | 1 | 387 | 1 | 387 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002266646.1 | 0 | 25 | 387 | 25 | 387 | PREDICTED: hypothetical protein [Vitis vinifera] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EC939466 | 267 | 26 | 286 | 0 |
CO983212 | 232 | 155 | 385 | 0 |
EC927952 | 183 | 174 | 356 | 0 |
GE475605 | 296 | 93 | 385 | 0 |
GO363500 | 275 | 86 | 359 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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