| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01012820001 |
| Family | GT47 |
| Protein Properties | Length: 478 Molecular Weight: 54418.1 Isoelectric Point: 9.9584 |
| Chromosome | Chromosome/Scaffold: 11 Start: 5736757 End: 5739075 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 141 | 428 | 0 |
| KRFKVWTYREGAQPIFHEGPLTNIYAIEGQFIDEMDFIVGKSPFIAKHPDEAHAFFLPLSVVKVVQFLYLPITSPEDYSRKRLQRIVTDYVKVVADKYPY WNRSGGADHFMVSCHDWAPSVSYANPELFKNFIRVLCNANSSEGFRPGRDVSLPEVNLPAGELGPPHLGQPSNNRPVLAFFAGRAHGNIRKILFEHWKDQ DNEVLVHERLHKGQNYAKLMGQSKFCLCPSGYEVASPRVVEAIHAGCVPVIISNNYSLPFNDVLDWSQFSIQIPVAKIPEIKTILLGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 478 Download |
| MAALSSCPAT LFLLPAVVVL LYLFFSPLNE NHLTYFLSSS TVFNPTKTSH TTLPEVFLNE 60 SLSVSIYRIS KQKASSTVKV PMKIKSSLAR IEEDLARARA AIRKAVRSKN YSSDKKEAFI 120 PRGCIYRNPY AFHQSHIEMV KRFKVWTYRE GAQPIFHEGP LTNIYAIEGQ FIDEMDFIVG 180 KSPFIAKHPD EAHAFFLPLS VVKVVQFLYL PITSPEDYSR KRLQRIVTDY VKVVADKYPY 240 WNRSGGADHF MVSCHDWAPS VSYANPELFK NFIRVLCNAN SSEGFRPGRD VSLPEVNLPA 300 GELGPPHLGQ PSNNRPVLAF FAGRAHGNIR KILFEHWKDQ DNEVLVHERL HKGQNYAKLM 360 GQSKFCLCPS GYEVASPRVV EAIHAGCVPV IISNNYSLPF NDVLDWSQFS IQIPVAKIPE 420 IKTILLGISK NKYLKMQERV LRVRRHFVLN RPARPFDIIH MILHSLWLRR LNFGLPH* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-65 | 139 | 428 | 308 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABP03872.1 | 0 | 86 | 475 | 77 | 465 | Exostosin-like [Medicago truncatula] |
| GenBank | ABP03873.1 | 0 | 65 | 475 | 217 | 613 | Exostosin-like [Medicago truncatula] |
| EMBL | CAN76361.1 | 0 | 83 | 477 | 61 | 459 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI25537.1 | 0 | 1 | 477 | 1 | 477 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002263848.1 | 0 | 82 | 477 | 1 | 396 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
