| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01013121001 |
| Family | GT20 |
| Protein Properties | Length: 224 Molecular Weight: 25640.3 Isoelectric Point: 4.6052 |
| Chromosome | Chromosome/Scaffold: 2 Start: 8020588 End: 8023605 |
| Description | trehalose phosphatase/synthase 5 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 29 | 218 | 0 |
| VSQDRMIIVGNQLPLRAHRSSDGSGEWCFSWDEDSLLLQLKDGLGEDVEVLYVGCLREQIDPSEQDDVAQTLLETFKCVPAFIPPELFSKFYHGFCKQQL WPLFHYMLPLSPDLGGRFDRSLWQAYVSVNKIFADKVMEVITPDEDFVWVHDYHLMVLPTFLRKRFNRVKLGFFLHSPFPSSEIYRTLPA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 224 Download |
| MVSRSYSNLL DLLDDETSNS VTSDAPSSVS QDRMIIVGNQ LPLRAHRSSD GSGEWCFSWD 60 EDSLLLQLKD GLGEDVEVLY VGCLREQIDP SEQDDVAQTL LETFKCVPAF IPPELFSKFY 120 HGFCKQQLWP LFHYMLPLSP DLGGRFDRSL WQAYVSVNKI FADKVMEVIT PDEDFVWVHD 180 YHLMVLPTFL RKRFNRVKLG FFLHSPFPSS EIYRTLPALP LLL* 240 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0380 | OtsA | 1.0e-46 | 33 | 217 | 187 | + Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism] | ||
| PRK14501 | PRK14501 | 5.0e-51 | 33 | 217 | 189 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 4.0e-69 | 33 | 217 | 185 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| pfam00982 | Glyco_transf_20 | 2.0e-83 | 33 | 217 | 187 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PLN02205 | PLN02205 | 1.0e-129 | 1 | 223 | 252 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN61971.1 | 0 | 1 | 223 | 1 | 250 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI33857.1 | 0 | 1 | 223 | 1 | 223 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002277503.1 | 0 | 1 | 223 | 1 | 226 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002304347.1 | 0 | 1 | 223 | 1 | 248 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002326738.1 | 0 | 1 | 223 | 1 | 250 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 2e-17 | 118 | 223 | 75 | 174 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 2e-17 | 118 | 223 | 75 | 174 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 2e-17 | 118 | 223 | 75 | 174 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 2e-17 | 118 | 223 | 75 | 174 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1uqu_B | 2e-17 | 118 | 223 | 75 | 174 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX674803 | 240 | 1 | 213 | 0 |
| DB881643 | 217 | 7 | 223 | 0 |
| JZ018779 | 219 | 5 | 223 | 0 |
| FS071107 | 237 | 1 | 210 | 0 |
| EB084565 | 203 | 16 | 218 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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