| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01014123001 |
| Family | GT47 |
| Protein Properties | Length: 380 Molecular Weight: 43488.2 Isoelectric Point: 9.668 |
| Chromosome | Chromosome/Scaffold: 19 Start: 572713 End: 579099 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 2 | 304 | 0 |
| PAKFTYDLLWLFRNTYKETSNRTSNGSPVHRLIEQHSIDYWLWADLTAPESERLLKNVVRVHRQEEADLFYIPFFTTISFFLLEPEQWKPLYREALKWVT DQPAWKRSEGRDHILPVHHPWSFKTVRKSMKNAIWLLPDMDSTGNWYKPGQVSLEKDLILPYVPNVDLCDAKCSSESESKRKTLLFFRGRLKRNAGGKIR AKLMAELSGDDGVVIQEGTAGEGGKEAAQRGMRKSIFCLSPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGILDYRKIALFVSSSDAMQPGWLLTFL KSI | |||
| Full Sequence |
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| Protein Sequence Length: 380 Download |
| MPAKFTYDLL WLFRNTYKET SNRTSNGSPV HRLIEQHSID YWLWADLTAP ESERLLKNVV 60 RVHRQEEADL FYIPFFTTIS FFLLEPEQWK PLYREALKWV TDQPAWKRSE GRDHILPVHH 120 PWSFKTVRKS MKNAIWLLPD MDSTGNWYKP GQVSLEKDLI LPYVPNVDLC DAKCSSESES 180 KRKTLLFFRG RLKRNAGGKI RAKLMAELSG DDGVVIQEGT AGEGGKEAAQ RGMRKSIFCL 240 SPAGDTPSSA RLFDAIVSGC IPVIVSDELE LPFEGILDYR KIALFVSSSD AMQPGWLLTF 300 LKSISPAQIK EMQRNLAKYS RHFVYSSPAQ LLGPEDLVWR MMAGKLMNIK LHTRRLQRVV 360 RESRRLCTCD CKRANFTGP* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-64 | 5 | 304 | 308 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI20132.1 | 0 | 1 | 379 | 1 | 379 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197191.1 | 0 | 1 | 373 | 125 | 497 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002285599.1 | 0 | 1 | 379 | 135 | 513 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325382.1 | 0 | 1 | 377 | 125 | 501 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002520033.1 | 0 | 1 | 379 | 126 | 504 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EX131311 | 278 | 1 | 278 | 0 |
| EV550550 | 295 | 35 | 329 | 0 |
| FY793417 | 281 | 88 | 368 | 0 |
| DY810265 | 277 | 54 | 330 | 0 |
| HO804389 | 284 | 94 | 377 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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