| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01018468001 |
| Family | GH29 |
| Protein Properties | Length: 968 Molecular Weight: 108632 Isoelectric Point: 7.0138 |
| Chromosome | Chromosome/Scaffold: 16 Start: 14619669 End: 14632502 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH29 | 39 | 381 | 0 |
| PTASQLKWQQREIIMFFHFGMNTFTDSEWGTGQENPNLFNPTGLDARQWVSTAAEAGFSLVILTAKHHDGFCLWPSKYTDHSVVSSPWKNGHGDVVRDLT NAAKAQGNIDVGLYLSPWDRHDQRYGKNQEYNEYYLAQLQELLKQYGVIQEIWFDGAKGEDAANMSYYFEEWFEMVKELQSSINIFSDAGPDVRWVGNEN GFSGNTSWSTINRTLLSIGNGDNVGKLNKNIVDIILLRVYLSKTGVWACKLYVRHYNPEPINMDYLNTGDPQGTDWVPPECDVSIRPGWFWHASEQPKEL SQLLEIYYNSVGRNCVLLFNVPPNSTGLISEIDVQRLMEFKKA | |||
| GH29 | 542 | 842 | 0 |
| KSSQLKWQERELIMFLHFGVNTFTDSEWGTGHESPAIFNPTGLNASQWVEVAVEAGISLMILTAKHHDGFCLWPSKYTDHSVVSSPWRNGHGDVVRDLVT AAEARGVDVGLYLSPWDRHDRRYGKEKQYNEYYLAQLQELLHEYGNVREIWFDGAKGANAPNMSYDFGDWFAMVRELQTSINIFSDAGPDVRWVGNEKGF AGSTCWSTINRTSLSIGNASIVDYINTGDPKGTDWLPPECDVSIRPGWFWHKSQKPKKLSKLLEIYYNSVGRNCVLLFNVPPNTTGLISETDVQRLREFR N | |||
| Full Sequence |
|---|
| Protein Sequence Length: 968 Download |
| MAKSLYFLCI IALVQLLEFI PSCMTQFATT PPLPVLPIPT ASQLKWQQRE IIMFFHFGMN 60 TFTDSEWGTG QENPNLFNPT GLDARQWVST AAEAGFSLVI LTAKHHDGFC LWPSKYTDHS 120 VVSSPWKNGH GDVVRDLTNA AKAQGNIDVG LYLSPWDRHD QRYGKNQEYN EYYLAQLQEL 180 LKQYGVIQEI WFDGAKGEDA ANMSYYFEEW FEMVKELQSS INIFSDAGPD VRWVGNENGF 240 SGNTSWSTIN RTLLSIGNGD NVGKLNKNIV DIILLRVYLS KTGVWACKLY VRHYNPEPIN 300 MDYLNTGDPQ GTDWVPPECD VSIRPGWFWH ASEQPKELSQ LLEIYYNSVG RNCVLLFNVP 360 PNSTGLISEI DVQRLMEFKK AIDTTFSTNL AEKSSVDASS QRGGQHWIEI KAASGGLRFN 420 VIRIQEPIGL GQRIIGHEVY ADGKLIVEGT TVGHKRLHRL GDVVEATVVK VQILESKGVP 480 LVSSFGLHFD PFGQPNGTSV YKELRKKRKI GVDSWSNILG LKSAEGEVHF ITPPLPILPL 540 PKSSQLKWQE RELIMFLHFG VNTFTDSEWG TGHESPAIFN PTGLNASQWV EVAVEAGISL 600 MILTAKHHDG FCLWPSKYTD HSVVSSPWRN GHGDVVRDLV TAAEARGVDV GLYLSPWDRH 660 DRRYGKEKQY NEYYLAQLQE LLHEYGNVRE IWFDGAKGAN APNMSYDFGD WFAMVRELQT 720 SINIFSDAGP DVRWVGNEKG FAGSTCWSTI NRTSLSIGNA SIVDYINTGD PKGTDWLPPE 780 CDVSIRPGWF WHKSQKPKKL SKLLEIYYNS VGRNCVLLFN VPPNTTGLIS ETDVQRLREF 840 RNAVDTIFST NLVENGAIKA SSRRGGKDSD FGPENGLRFN VVRIQEAIGL GQRIKRHEIY 900 ADGKLVGKGT TVGHKRLHRL GGVVHARSLK VRILESRGVP LVSSFGLHFD PFWHPPHGHS 960 LSNGSRF* 1020 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00812 | Alpha_L_fucos | 5.0e-25 | 76 | 194 | 132 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| pfam01120 | Alpha_L_fucos | 1.0e-27 | 548 | 840 | 326 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 2.0e-28 | 548 | 840 | 334 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 4.0e-55 | 43 | 487 | 471 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| COG3669 | COG3669 | 2.0e-56 | 545 | 947 | 436 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI24481.1 | 0 | 1 | 967 | 1 | 967 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002270630.1 | 0 | 41 | 495 | 21 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270630.1 | 0 | 542 | 967 | 20 | 474 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 24 | 504 | 1 | 470 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 532 | 955 | 7 | 461 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 536 | 948 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_B | 0 | 34 | 488 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 536 | 948 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 34 | 488 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3mo4_B | 0 | 541 | 943 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
