| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01020746001 |
| Family | AA7 |
| Protein Properties | Length: 514 Molecular Weight: 57806.2 Isoelectric Point: 8.1646 |
| Chromosome | Chromosome/Scaffold: 12 Start: 2402145 End: 2404091 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 151 | 471 | 0 |
| GGYGTLLRKYGLAADNIIDAYIVDSNGTLLNRESMGEDLFWAIRGGGGASFGIIVSWKIKLVPVPSTVTVFRVTRTLEQDAEKILLKWQQVADKLHEDLF IRVYVQAVNGSQEGERTISSTYESLFLGNTSGLLSLMNESFPELGLAADDCNETSWIESVLYFAGFSGQPLDEPIPETGLQGIWKLFYQVKNATALMIIS PYGGRMNEIPETETPFPHRKGSLYSIQYVVAWLEEGKKVSKRHIDWARKLHKYMAPYVSKSPRAAYLNYRDLDLGRNKNGNTSYAQASIWGLKYYKINFN RLVQVKTKVDPSNFFRNEQSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 514 Download |
| MGSSSSAETY ILVFTLLFSS VSWAASSSVH QNFLQCLTLN SNSSTPITKV LYTPKNSSYE 60 TVLDFSIQNL RFTSSCTPKP QIIVTPLHVS HIQAAVICSK KYGLQIRARS GGHDYEGLSY 120 VSEVPFIIVD LLELRSINVD VEDGSAWVEA GGYGTLLRKY GLAADNIIDA YIVDSNGTLL 180 NRESMGEDLF WAIRGGGGAS FGIIVSWKIK LVPVPSTVTV FRVTRTLEQD AEKILLKWQQ 240 VADKLHEDLF IRVYVQAVNG SQEGERTISS TYESLFLGNT SGLLSLMNES FPELGLAADD 300 CNETSWIESV LYFAGFSGQP LDEPIPETGL QGIWKLFYQV KNATALMIIS PYGGRMNEIP 360 ETETPFPHRK GSLYSIQYVV AWLEEGKKVS KRHIDWARKL HKYMAPYVSK SPRAAYLNYR 420 DLDLGRNKNG NTSYAQASIW GLKYYKINFN RLVQVKTKVD PSNFFRNEQS IPPLSSWKII 480 FPFLKKLFFE LLLKWCMVYF LQNFGKSMHS FLE* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN02805 | PLN02805 | 0.007 | 80 | 259 | 224 | + D-lactate dehydrogenase [cytochrome] | ||
| pfam01565 | FAD_binding_4 | 8.0e-15 | 80 | 181 | 139 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| COG0277 | GlcD | 6.0e-17 | 80 | 231 | 196 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam08031 | BBE | 6.0e-18 | 415 | 472 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN63059.1 | 0 | 1 | 477 | 1 | 533 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI22014.1 | 0 | 1 | 477 | 1 | 410 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI22015.1 | 0 | 1 | 513 | 1 | 513 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002277294.1 | 0 | 1 | 477 | 1 | 533 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002277310.1 | 0 | 1 | 477 | 1 | 534 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 31 | 474 | 5 | 513 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 26 | 474 | 6 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 26 | 474 | 6 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 28 | 474 | 6 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 28 | 474 | 6 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |
