| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01022253001 |
| Family | GH17 |
| Protein Properties | Length: 1074 Molecular Weight: 122199 Isoelectric Point: 8.1844 |
| Chromosome | Chromosome/Scaffold: 7 Start: 17857238 End: 17870799 |
| Description | tRNAHis guanylyltransferase |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH17 | 27 | 345 | 0 |
| LGVNWGTQASHILQPSIVVRLLKDNGINKVKLFDADSWTVNALAGSGIEVMVGIPNKDLQRYNSYKKAKHWVEKNVTKHLYDGGVDIRYVAVGNEPFLTS YNGSFLNTTFPALSNIQKALDEAGHGDKIKATIPLNADVYESATNKPSDGQFRKDIKDLMIKIVKLLHEKKSAFVVNIYPFLSLYQNPDFPLDFAFFNGG GNPTEDKGVQYTNVFDANHDTLVWALRKAGVPDLKILVGEIGWPTDGDKNANLKLARRFYDGLLKKLADGKGTPLRPGRLDVYLFGLIDENMKSVAPGSF ERHWGIFFFDGKPKFPMDF | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1074 Download |
| MARAGAFVWA FLSVVLLAFN TSHGDALGVN WGTQASHILQ PSIVVRLLKD NGINKVKLFD 60 ADSWTVNALA GSGIEVMVGI PNKDLQRYNS YKKAKHWVEK NVTKHLYDGG VDIRYVAVGN 120 EPFLTSYNGS FLNTTFPALS NIQKALDEAG HGDKIKATIP LNADVYESAT NKPSDGQFRK 180 DIKDLMIKIV KLLHEKKSAF VVNIYPFLSL YQNPDFPLDF AFFNGGGNPT EDKGVQYTNV 240 FDANHDTLVW ALRKAGVPDL KILVGEIGWP TDGDKNANLK LARRFYDGLL KKLADGKGTP 300 LRPGRLDVYL FGLIDENMKS VAPGSFERHW GIFFFDGKPK FPMDFSGKGL DKFLEPAKGV 360 IYLEPKWCVL NRDAVKNMTQ NQDVEACNFN GMGKITTKNA STGTCLFPVQ MMSAGEKLIG 420 YGVSVTGFMG LFQLYCIHQV FGDCSVRSQE QKEEFIGEWD MANSKYEYVK SFEVEDEVMP 480 PNLIVVRIDG RGFRRFSEVH EFEKPNDERA LNLMNSCAAA MLEEYPDIVF SYGFSDEYSF 540 VFKKTTKFYQ RRASKIVSLV VSFFTSIYTT KWKEFFPHKE LRYPPSFRAW VICCASMEVL 600 QTYLAWRQND CHINNQYNTC FWMLVKCGKT EEEAQEVLKG THKQEKNELL FQQFGINYKN 660 LPSMFRQGSC VCKTQVEAIV KYSENGTPVK RLRRKPIIVH SDNIAARSFW NEHPFLLKEL 720 GDFREDINNI KPEYVKSFQF ENKLMPLTWI VVRIDGCHFH RFSEVHEFEK PNDEQALNLM 780 NSCAVAVLEQ FKDVIFSYGV SDEYSFVLKK DSQFYQRRGS EIVTALVSYF TSIYVMKWKE 840 FFPQKELKYP PCFDGRAVLY PTSEILRDYL TWRQVDCHIN NQYNTCFWML VKSGKSKSEA 900 QAYLKGTQAR EKNEVLLQQF GIDYNTLPLM FRQGSSAFWN EEEKTGMYEN GASAEKSGKK 960 VVVEQCNIIE QSFWEAHPSI LNEKPHMPQL RSSGTSTIVQ NSFETTPLSK TLKLAHTRTS 1020 PSPSPCRTAG TGKETDRKLG SALPRPASSS PGTPANQRKD LQQSHDTSPP LET* 1080 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04446 | Thg1 | 4.0e-62 | 465 | 593 | 131 | + tRNAHis guanylyltransferase. The Thg1 protein from Saccharomyces cerevisiae is responsible for adding a GMP residue to the 5' end of tRNA His. The catalytic domain Thg1 contains a RRM (ferredoxin) fold palm domain, just like the viral RNA-dependent RNA polymerases, reverse transcriptases, family A and B DNA polymerases, adenylyl cyclases, diguanylate cyclases (GGDEF domain) and the predicted polymerase of the CRISPR system. Thg1 possesses an active site with three acidic residues that chelate Mg++ cations. Thg1 catalyzes polymerization similar to the 5'-3' polymerases. | ||
| COG4021 | COG4021 | 1.0e-63 | 733 | 978 | 253 | + Uncharacterized conserved protein [Function unknown] | ||
| pfam04446 | Thg1 | 1.0e-65 | 731 | 861 | 131 | + tRNAHis guanylyltransferase. The Thg1 protein from Saccharomyces cerevisiae is responsible for adding a GMP residue to the 5' end of tRNA His. The catalytic domain Thg1 contains a RRM (ferredoxin) fold palm domain, just like the viral RNA-dependent RNA polymerases, reverse transcriptases, family A and B DNA polymerases, adenylyl cyclases, diguanylate cyclases (GGDEF domain) and the predicted polymerase of the CRISPR system. Thg1 possesses an active site with three acidic residues that chelate Mg++ cations. Thg1 catalyzes polymerization similar to the 5'-3' polymerases. | ||
| COG4021 | COG4021 | 8.0e-71 | 462 | 700 | 240 | + Uncharacterized conserved protein [Function unknown] | ||
| pfam00332 | Glyco_hydro_17 | 2.0e-75 | 27 | 345 | 322 | + Glycosyl hydrolases family 17. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000287 | magnesium ion binding |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| GO:0006400 | tRNA modification |
| GO:0008193 | tRNA guanylyltransferase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN62815.1 | 0 | 461 | 941 | 1 | 481 | hypothetical protein [Vitis vinifera] |
| EMBL | CAN62815.1 | 0 | 727 | 983 | 1 | 259 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI21529.1 | 0 | 1 | 1073 | 1 | 1073 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002275722.1 | 0 | 460 | 719 | 266 | 523 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002275722.1 | 0 | 461 | 987 | 1 | 527 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ote_B | 0 | 731 | 983 | 5 | 267 | A Chain A, Structure Of The Amylomaltase From Thermus Thermophilus Hb8 In Space Group P21212 |
| PDB | 3ote_B | 0 | 461 | 719 | 1 | 267 | A Chain A, Structure Of The Amylomaltase From Thermus Thermophilus Hb8 In Space Group P21212 |
| PDB | 3ote_A | 0 | 731 | 983 | 5 | 267 | A Chain A, Structure Of The Amylomaltase From Thermus Thermophilus Hb8 In Space Group P21212 |
| PDB | 3ote_A | 0 | 461 | 719 | 1 | 267 | A Chain A, Structure Of The Amylomaltase From Thermus Thermophilus Hb8 In Space Group P21212 |
| PDB | 3otd_B | 0 | 731 | 983 | 5 | 267 | A Chain A, Structure Of The Amylomaltase From Thermus Thermophilus Hb8 In Space Group P21212 |
