| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01022479001 |
| Family | GT47 |
| Protein Properties | Length: 468 Molecular Weight: 53830.1 Isoelectric Point: 9.4462 |
| Chromosome | Chromosome/Scaffold: 8 Start: 3527773 End: 3534417 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 122 | 398 | 0 |
| RSFKIYCYPHKRDDPFANALLPVDFEPGGNYASESYFKKVLMKSHFITKDPSKADLFFLPFSIARLRHDPRVGVGGIQDFIRDYIFNISQNYPYWNQTGG ADHFYVACHSIGRSAMEKADEVKLNAIQVVCSSSYFLSGYIAHKDASLPQIWPRQGDPPDLALSERKKLAFFAGSINSPVRERLLQVWRNDSEISVHFGR LTTPYADELLGSKFCLHVKGFEINTARIADSLYYGCVPVIIANHYDLPFADILNWKSFSIVVATLDIPLLKQVLKGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 468 Download |
| MARSFFILYH FSGRRFSDSF RGFFFIPTIL ALITSLFILF YISSTSNLFT HPQETHLQVL 60 KSALGSSAFS PPSHQFMRVP AETPHLSRGF EFNTKGRFVL LWCTIIRHDR NLFVENYKEM 120 NRSFKIYCYP HKRDDPFANA LLPVDFEPGG NYASESYFKK VLMKSHFITK DPSKADLFFL 180 PFSIARLRHD PRVGVGGIQD FIRDYIFNIS QNYPYWNQTG GADHFYVACH SIGRSAMEKA 240 DEVKLNAIQV VCSSSYFLSG YIAHKDASLP QIWPRQGDPP DLALSERKKL AFFAGSINSP 300 VRERLLQVWR NDSEISVHFG RLTTPYADEL LGSKFCLHVK GFEINTARIA DSLYYGCVPV 360 IIANHYDLPF ADILNWKSFS IVVATLDIPL LKQVLKGISL NEYLMLQSNV LKVRNHFQWH 420 VSPVDYDAFY MVMYELWLRR SSVRVPLIVL NANFKGKMKC FTPSSWI* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-66 | 120 | 398 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABD28410.1 | 0 | 26 | 447 | 26 | 483 | Exostosin-like [Medicago truncatula] |
| EMBL | CBI39073.1 | 0 | 1 | 467 | 1 | 467 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265438.1 | 0 | 1 | 447 | 1 | 445 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325425.1 | 0 | 120 | 449 | 1 | 326 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002525728.1 | 0 | 120 | 445 | 1 | 326 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
