| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01022867001 |
| Family | GT24 |
| Protein Properties | Length: 1716 Molecular Weight: 193345 Isoelectric Point: 6.2934 |
| Chromosome | Chromosome/Scaffold: 12 Start: 18573041 End: 18645328 |
| Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT24 | 1408 | 1655 | 0 |
| INIFSIASGHLYERFLKIMILSVLKNSNRPVKFWFIKNYLSPQFKDVIPHMAQEYGFEYELITYKWPTWLHKQKEKQRIIWAYKILFLDVIFPLSLEKVI FVDADQIVRADMGELYDMDIKGRPLAYTPFCDNNKDMDGYRFWRQGFWKDHLRGKPYHISALYVVDLVKFRETAAGDNLRVFYETLSKDPNSLSNLDQDL PNFAQHTVPIFSLPQEWLWCESWCGNATKSKAKTIDLCNNPMTKEPKL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1716 Download |
| MGTHFRSGFW VLVVLACASL CWNGSVVADN RRPKNVQVAV RAKWSGTPLL LEAGELLAKE 60 RKDLFWRFIE VWLSAEKDDA DSFTAKDCLK KIVKYGHSLL SESLASLFEF SLTLRSASPR 120 LVLYRQLAEE SLSSFPLTDE NPFLVGVNPK SPGGKCCWVD TGGSLFFDGA ELLLWLRSPT 180 ESGSFQPPEL FDFDHIHFGS SVSSPVTILY GALGTDCFRE FHVILAEAAK EGKVKYVVRP 240 VLPSGCETKI GHCGVVGTKD PLNLGGYGVE LALKNMEYKA MDDSMIKKGV TLEDPRTEDL 300 SQEVRGFIFS KILERKPELS SEIMAFRDYL LSSTISDTLD VWELKDLGHQ TAQRIVHASD 360 PLQSMQEINQ NFPSVVSSLS RMKLNDSVKD EIIANQRMIP PGKSLMALNG AIINIDDIDL 420 YLLMDMVHQE LSLADQFSKL KIPQSTVQKL LATQPPPESN MFRIDFRSTH VHYLNDLEED 480 ARYRRWRSNI NEILMPVFPG QLRYIRKNLF HAVYVLDPAS VCGLESVDMI ISMYENNLPM 540 RFGVILYSTT FIKMVEMSGG ELQVSKAEDG QVEEDISNLI IRLFIYIKED QGTQMAFQFL 600 SNVNRLRTES EDSSGALEVH HVEGAFVETL LPKAKTPPQD ILLKLQKEQN FKELSQESSI 660 FVLKLGLSKL QCCLLMNGLV FDTNEDALIN AMNDELPRIQ EQVYYGHISS HTNVLEKFLS 720 ESGIQRYNPQ IIADTKVKPR FISLASSVLG GESVLNDISY LHSPDTIDDL KPVTHLLAVD 780 ITSRKGMKLL REGIRYLIGG PKSSRLGVLF SVNPGPDSPS LLFVKVFEIT ASSYSHKKKV 840 LNFLDQLCSF YASEYMLASS IVVEGTQAFI DKVCELADAN GIPSKGYKSI LSEFSVDEFR 900 GHLNKVAQFL YRQLGLESGS NAVITNGRVM VAVDEGTILS HDLLLLESVE FKQRIKFILE 960 IIEEVKWQDM DPDMLTSKFI SDVIMFVSSA MATRDRSSES ARFEILNAKY SAVLLNNGNS 1020 SIHIDAVVDP LSPSGQKLAS LLRVLWKYIQ PSMRIILNPL SSLVDIPLKN YYRYVVPTMD 1080 DFSSTDYTIN GPKAFFANMP LSKTLTMNLD VPEPWLVEPV IAVHDLDNIL LENLGDTRTL 1140 QAVFELEALL LTGHCSEKDH DPPRGLQLIL GTKSTPHLVD TLVMANLGYW QMKVFPGVWY 1200 LQLAPGRSSE LYLLKEGGVG SQDSPLSKRI TINDLRGKLV HLEVVKKKGK EHENLLISSD 1260 DNHLQDGKKG NHDSWNSNLL KWASGFISGG EQLKKSESTS VSLVLDHIVY QTFAMGSALV 1320 VTQVSLIKCM IQVHALINFG GCVKIPALIG SQMQRTYNKL NKKSTIILNT PLKAFKRSSV 1380 YFITFLYTLE GSLILLGHGK GGRRGKTINI FSIASGHLYE RFLKIMILSV LKNSNRPVKF 1440 WFIKNYLSPQ FKDVIPHMAQ EYGFEYELIT YKWPTWLHKQ KEKQRIIWAY KILFLDVIFP 1500 LSLEKVIFVD ADQIVRADMG ELYDMDIKGR PLAYTPFCDN NKDMDGYRFW RQGFWKDHLR 1560 GKPYHISALY VVDLVKFRET AAGDNLRVFY ETLSKDPNSL SNLDQDLPNF AQHTVPIFSL 1620 PQEWLWCESW CGNATKSKAK TIDLCNNPMT KEPKLQGARR IVPEWQDLDF EARQFTAKVS 1680 GEVDPQEPVT PPKQSQDPIT DSSPEEDDQE SKSEL* 1740 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01501 | Glyco_transf_8 | 7.0e-6 | 1412 | 1630 | 231 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
| cd04194 | GT8_A4GalT_like | 8.0e-15 | 1408 | 1624 | 227 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
| cd00505 | Glyco_transf_8 | 8.0e-57 | 1408 | 1655 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
| pfam06427 | UDP-g_GGTase | 4.0e-80 | 981 | 1186 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
| cd06432 | GT8_HUGT1_C_like | 2.0e-174 | 1408 | 1655 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
| GO:0006486 | protein glycosylation |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD28382.1 | 0 | 31 | 1709 | 35 | 1625 | putative UDP-glucose:glycoprotein glucosyltransferase [Oryza sativa Japonica Group] |
| EMBL | CBI23772.1 | 0 | 1 | 1715 | 1 | 1715 | unnamed protein product [Vitis vinifera] |
| GenBank | EEC73742.1 | 0 | 31 | 1709 | 35 | 1672 | hypothetical protein OsI_08377 [Oryza sativa Indica Group] |
| RefSeq | XP_002268972.1 | 0 | 1 | 1300 | 1 | 1292 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
| RefSeq | XP_002268972.1 | 0 | 1407 | 1715 | 1303 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
