| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01027076001 |
| Family | GH18 |
| Protein Properties | Length: 436 Molecular Weight: 49354.5 Isoelectric Point: 9.7444 |
| Chromosome | Chromosome/Scaffold: 15 Start: 18144275 End: 18149907 |
| Description | Glycosyl hydrolase superfamily protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 107 | 426 | 9.4e-34 |
| YPVLAYITPWNNKGYDLAKSFNSKFTHLSPIWYDLRSQGTNLVLEGRHNADIGWITELRMKGDAWVIPRVVLEAIPKELLRKKKQRDKAIEMIITECKEM DYDGIVLESWSRWAAYGILHDPVMRNMALQFIKQLGQALHSVSSEKNGKQGLQLIYVIGPPRSEKLQEHDFGPADLRSLSDYVDGFSLMTYDFSGPHNPG PNAPLKWIHSTLQLLLGSVGKSDQSLARKILLGINFYGNDFALSKGGGGGAITGRDYLSLLDKHKPVLQWEKNSGEHLFFYSDDHHAKHAVFYPSLMSIF LRLEEARSWGVGISIWEIGQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 436 Download |
| MAKRREGRVP SSSDRREDRV EASKRAIRRG GDSASSPKIN IVLFLFVVIA PAIAVLVYRI 60 RYAPRTNRAL SSYVHQQGLV KADVNYQEIL TENSKVSKNM SQRHYTYPVL AYITPWNNKG 120 YDLAKSFNSK FTHLSPIWYD LRSQGTNLVL EGRHNADIGW ITELRMKGDA WVIPRVVLEA 180 IPKELLRKKK QRDKAIEMII TECKEMDYDG IVLESWSRWA AYGILHDPVM RNMALQFIKQ 240 LGQALHSVSS EKNGKQGLQL IYVIGPPRSE KLQEHDFGPA DLRSLSDYVD GFSLMTYDFS 300 GPHNPGPNAP LKWIHSTLQL LLGSVGKSDQ SLARKILLGI NFYGNDFALS KGGGGGAITG 360 RDYLSLLDKH KPVLQWEKNS GEHLFFYSDD HHAKHAVFYP SLMSIFLRLE EARSWGVGIS 420 IWEIGQGLDY FFDLL* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00704 | Glyco_hydro_18 | 3.0e-13 | 184 | 426 | 263 | + Glycosyl hydrolases family 18. | ||
| COG3858 | COG3858 | 4.0e-21 | 185 | 435 | 257 | + Predicted glycosyl hydrolase [General function prediction only] | ||
| cd02874 | GH18_CFLE_spore_hydrolase | 9.0e-30 | 109 | 435 | 346 | + Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis. | ||
| smart00636 | Glyco_18 | 4.0e-30 | 109 | 426 | 360 | + Glyco_18 domain. | ||
| cd02876 | GH18_SI-CLP | 2.0e-150 | 105 | 435 | 336 | + Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome. SI-CLP has a glycosyl hydrolase family 18 (GH18) domain but lacks a chitin-binding domain. The catalytic amino acids of the GH18 domain are not conserved in SI-CLP, similar to the chitolectins YKL-39, YKL-40, and YM1/2. Human SI-CLP is sorted to late endosomes and secretory lysosomes in alternatively activated macrophages. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN82499.1 | 0 | 1 | 435 | 1 | 516 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI40499.1 | 0 | 1 | 435 | 1 | 435 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_192013.1 | 0 | 1 | 435 | 1 | 430 | glycosyl hydrolase family 18 protein [Arabidopsis thaliana] |
| RefSeq | XP_002320856.1 | 0 | 61 | 435 | 27 | 399 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523373.1 | 0 | 1 | 435 | 1 | 432 | chitinase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3bxw_A | 0 | 74 | 435 | 45 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
| PDB | 3bxw_B | 0 | 74 | 435 | 45 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
| PDB | 3cz8_B | 0.000005 | 272 | 424 | 163 | 308 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
| PDB | 3cz8_A | 0.000005 | 272 | 424 | 163 | 308 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
