| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01028371001 |
| Family | AA3 |
| Protein Properties | Length: 590 Molecular Weight: 65195.3 Isoelectric Point: 8.8923 |
| Chromosome | Chromosome/Scaffold: 7 Start: 6757378 End: 6760531 |
| Description | Long-chain fatty alcohol dehydrogenase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 263 | 585 | 9.1e-29 |
| KWSTDHKLPLFGSSEYLSAMDTVWKRIGVTEKCTEEGFQNQVLRKGCENLGLDVESIPRNSSENHYCGSCAYGCTRGDKQGTQSTWLVDAVGCGAVILTG CKAEKLIFKEKKNGRKRRKCSGVIVASSSKNVTKKLQIEARVTVSACGSLLTPPLLLSSGLENPHIGKNLHLHPVLMVWGYFPEGIQSTGNNKGAGEVKV ERRIKYRLHPADKENLRVGLRQALRILIAAGAVEVGTYRRGPCSRGDHWTLYCSAHQMGSCRMGATEEEGAVDENGETWEAKGLFVCDGSVLPSAVGINP MITIQTTAYCISKRIAESLKKQE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 590 Download |
| MGKESNREEG HGHPLLRGGW RKGSYSHGFS SSQIQALASI CETLIPPLHL ESISKENPPE 60 ALYSFYKASG SQFPVPDEAA ELLKKRGLPE GVMLVSIVLK ILSTRLGTLL LCGFLCLGWK 120 WPFILKFSEI SLEKREQVLK NWSRQRFLFP LRLFFAIMKI FCFFIFFSRT DDNLENPAWD 180 AIGYHVETKE YVKKPPKERP IRKGIVETMY ENDSTLVQSL SQRGIKVIED QKNICKIKCD 240 VVIIGSGCGG GVTAAVLASS GYKWSTDHKL PLFGSSEYLS AMDTVWKRIG VTEKCTEEGF 300 QNQVLRKGCE NLGLDVESIP RNSSENHYCG SCAYGCTRGD KQGTQSTWLV DAVGCGAVIL 360 TGCKAEKLIF KEKKNGRKRR KCSGVIVASS SKNVTKKLQI EARVTVSACG SLLTPPLLLS 420 SGLENPHIGK NLHLHPVLMV WGYFPEGIQS TGNNKGAGEV KVERRIKYRL HPADKENLRV 480 GLRQALRILI AAGAVEVGTY RRGPCSRGDH WTLYCSAHQM GSCRMGATEE EGAVDENGET 540 WEAKGLFVCD GSVLPSAVGI NPMITIQTTA YCISKRIAES LKKQEFLAD* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01810 | betA | 0.002 | 465 | 587 | 136 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| TIGR03970 | Rv0697 | 8.0e-9 | 465 | 581 | 124 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| COG2303 | BetA | 2.0e-13 | 459 | 566 | 117 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| pfam05199 | GMC_oxred_C | 6.0e-25 | 465 | 573 | 119 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| pfam00732 | GMC_oxred_N | 1.0e-56 | 264 | 437 | 176 | + GMC oxidoreductase. This family of proteins bind FAD as a cofactor. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI23676.1 | 0 | 34 | 584 | 1 | 567 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI37146.1 | 0 | 1 | 589 | 1 | 589 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002272123.1 | 0 | 1 | 446 | 1 | 497 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002272123.1 | 0 | 454 | 589 | 570 | 731 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311685.1 | 0 | 13 | 446 | 6 | 515 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1b8s_A | 0.00005 | 518 | 588 | 442 | 503 | A Chain A, Cholesterol Oxidase From Streptomyces Glu361gln Mutant |
| PDB | 2gew_A | 0.00006 | 518 | 588 | 442 | 503 | A Chain A, Cholesterol Oxidase From Streptomyces Glu361gln Mutant |
| PDB | 1n4w_A | 0.00006 | 518 | 588 | 442 | 503 | A Chain A, Cholesterol Oxidase From Streptomyces Glu361gln Mutant |
| PDB | 1n4v_A | 0.00006 | 518 | 588 | 442 | 503 | A Chain A, Cholesterol Oxidase From Streptomyces Glu361gln Mutant |
| PDB | 1n4u_A | 0.00006 | 518 | 588 | 442 | 503 | A Chain A, Cholesterol Oxidase From Streptomyces Glu361gln Mutant |
