| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01030133001 |
| Family | GT47 |
| Protein Properties | Length: 635 Molecular Weight: 73374.2 Isoelectric Point: 8.0969 |
| Chromosome | Chromosome/Scaffold: 12 Start: 10124569 End: 10129564 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 307 | 587 | 0 |
| KLFKIFIYKEGEPPLFHNGPCKSIYSIEGVFFSLMEGDTHFRTQDPDEAHVYFLPFSVVMIIHHLFDPIVRDKYVMKHVVSDYVKVISQKYRYWNRSLGA DHFMLSCHDWGPRATWYVPQLYYNSIRLLCNANTSECFNPRKDASIPEINLIDGETIGLTGGLPPSKRTILAFFAGGLHGRIRPALLQHWKEKDEQVQVY ETLPEGLSYPDLMKKSKYCICPSGHEVASPRIVEAIYAECVPVLISQHYVLPFSDVLDWGSFSIQVSVNEIPNLKKILLGI | |||
| Full Sequence |
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| Protein Sequence Length: 635 Download |
| MKTMNKKERS TQHYSSSQKI LFVGEGDFSF SACLARQFGS AVNMVATSLD PEEMVYTKHW 60 SCETHLEELK RLGCLVLHEV DVKEMSRHPT LIHMEFDFIV FNFPHAGHFP WLCERNVQLI 120 KMHRKLLKAF FESASEMLSS GGEVHVTHRD DFPYNRWKVE KLAKGAGLYL KEKVEFQKDY 180 PGYHNKRGGG IKSNKTFPLK DSYTFKFSVI TWESKDDDDE DNDAMRQKEF MNPGNGLNEK 240 SVRERLRPRD AELERVEAGL ARARALIREG TTNWSSISAP VGADYVPQGD IYRNATAFHR 300 SYLLMEKLFK IFIYKEGEPP LFHNGPCKSI YSIEGVFFSL MEGDTHFRTQ DPDEAHVYFL 360 PFSVVMIIHH LFDPIVRDKY VMKHVVSDYV KVISQKYRYW NRSLGADHFM LSCHDWGPRA 420 TWYVPQLYYN SIRLLCNANT SECFNPRKDA SIPEINLIDG ETIGLTGGLP PSKRTILAFF 480 AGGLHGRIRP ALLQHWKEKD EQVQVYETLP EGLSYPDLMK KSKYCICPSG HEVASPRIVE 540 AIYAECVPVL ISQHYVLPFS DVLDWGSFSI QVSVNEIPNL KKILLGIPQD RYIRMQERVK 600 QVQQHFVVNN PPKRFDVFHM IIHSIWLRRL NVAI* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-68 | 305 | 587 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam10354 | DUF2431 | 4.0e-70 | 21 | 188 | 169 | + Domain of unknown function (DUF2431). This is the N-terminal domain of a family of proteins found from plants to humans. The function is not known. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI28482.1 | 0 | 1 | 634 | 1 | 634 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_187419.1 | 0 | 226 | 634 | 70 | 469 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002264111.1 | 0 | 305 | 634 | 1 | 330 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002320537.1 | 0 | 250 | 632 | 8 | 391 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524592.1 | 0 | 252 | 634 | 3 | 386 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD546223 | 266 | 369 | 634 | 0 |
| GW864815 | 318 | 321 | 634 | 0 |
| EH682902 | 232 | 404 | 634 | 0 |
| FE523338 | 283 | 282 | 563 | 0 |
| GE475605 | 292 | 344 | 632 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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