| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01030134001 |
| Family | GT47 |
| Protein Properties | Length: 417 Molecular Weight: 48236.2 Isoelectric Point: 8.6465 |
| Chromosome | Chromosome/Scaffold: 12 Start: 10130090 End: 10132198 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 87 | 367 | 0 |
| KLFKIYVYEEGEPPMFHNGPCKSIYSTEGRFIHEMEKGSVYRTTDPDQALLYFLPFSVVMMVQYLYVPDSHEIHAIEKTVIDYINLISHNHPFWNRSLGA DHFMLSCHDWGPRASTSVPYLYNNSIRVLCNANTSEGFNPSKDVSFPEIHLRTGEMSGPLGGLSPSRRPILGFFAGRLHGHIRYLLLEQWKDKDKDLQVY DQLPNGLSYDSMLKKSRFCLCPSGYEVASPRVVEAIYAECVPVLISDNYVPPFNDVLNWKSFAVQVQVRDIANIKRILMGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 417 Download |
| MQMHCFVGCS DSLGLASYEK KQETWKDKRY SKLERLEAGL ARARSSIREA ARNGSLKSTH 60 EDPDYVPQGP IYRNANAFHR SYLEMEKLFK IYVYEEGEPP MFHNGPCKSI YSTEGRFIHE 120 MEKGSVYRTT DPDQALLYFL PFSVVMMVQY LYVPDSHEIH AIEKTVIDYI NLISHNHPFW 180 NRSLGADHFM LSCHDWGPRA STSVPYLYNN SIRVLCNANT SEGFNPSKDV SFPEIHLRTG 240 EMSGPLGGLS PSRRPILGFF AGRLHGHIRY LLLEQWKDKD KDLQVYDQLP NGLSYDSMLK 300 KSRFCLCPSG YEVASPRVVE AIYAECVPVL ISDNYVPPFN DVLNWKSFAV QVQVRDIANI 360 KRILMGISQT QYLRMYRRVK QVQRHFMVNA APQRFDVFHM TIHSIWLRRL NIRIQD* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-65 | 85 | 367 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAU04753.1 | 0 | 80 | 416 | 7 | 343 | EXO [Cucumis melo] |
| EMBL | CBI28483.1 | 0 | 1 | 416 | 1 | 416 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002264076.1 | 0 | 85 | 416 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002320538.1 | 0 | 85 | 416 | 1 | 332 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524591.1 | 0 | 28 | 416 | 116 | 504 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DT001362 | 234 | 101 | 334 | 0 |
| EG631371 | 249 | 168 | 416 | 0 |
| GW864815 | 305 | 101 | 404 | 0 |
| FE523338 | 285 | 65 | 348 | 0 |
| CX643922 | 246 | 171 | 416 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
