| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01035630001 |
| Family | GT47 |
| Protein Properties | Length: 619 Molecular Weight: 70130.4 Isoelectric Point: 9.7011 |
| Chromosome | Chromosome/Scaffold: 4 Start: 2835735 End: 2842423 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 310 | 542 | 0 |
| NTLKVYTYREGERPVFHQPPIKGIYASEGWFMKLMQANKKFVTKNGRKAHLFYLPFSSLMLEEALYVPNSHSRKNLEQYLKNYLDMIGAKYPFWNRTGGA DHFLVACHDWAPSETLKLMANSIRALCNSDIREGFKLGKDVSLPETCVRIPQNPLRQLGGKPPSQRRILAFFAGSMHGYVRPILLKYWENKDPDMKIYGR MPKAKKGTMNYIQHMKSSKYCICAKGYEVNSPR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 619 Download |
| MGHKFRYLWQ VEARHLLWLI GTVFSVVFVV QYFELPYGDV LSSLFSAGDI PAPGKTSLPS 60 SDSFNAETME GNNEGPKNDF ASVMNGALDK SFGLDEDNKN VTVEKVNNSG NRSALKNASK 120 HESSLYLENI TADSNSSLGK IQEDDMALLS QRSERSGVGL ISPLPALPQI ISSSNTTSLT 180 NLDPHPITLP PERSSVEEDA AHTLNKDEKA ETSQKDLTLS NRSSISVPAL ETRPELPAVT 240 TISEMNDLLV QSRASSRSMK PRWSSAVDKE LLYAKSQIEN APIIKNDPGL HASLYRNVSV 300 FKRSYELMEN TLKVYTYREG ERPVFHQPPI KGIYASEGWF MKLMQANKKF VTKNGRKAHL 360 FYLPFSSLML EEALYVPNSH SRKNLEQYLK NYLDMIGAKY PFWNRTGGAD HFLVACHDWA 420 PSETLKLMAN SIRALCNSDI REGFKLGKDV SLPETCVRIP QNPLRQLGGK PPSQRRILAF 480 FAGSMHGYVR PILLKYWENK DPDMKIYGRM PKAKKGTMNY IQHMKSSKYC ICAKGYEVNS 540 PRKDIPNLKS ILLSIPEKSY LEIQMRVKQV QQHFLWHAKP VKYDVFHMIL HSVWYNRVLQ 600 IRVRPKQLLG RNKDCFWS* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-43 | 312 | 542 | 251 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI20855.1 | 0 | 1 | 618 | 1 | 618 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002280595.1 | 0 | 1 | 602 | 1 | 661 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002281263.1 | 0 | 1 | 610 | 1 | 675 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002309547.1 | 0 | 185 | 604 | 10 | 471 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002324801.1 | 0 | 245 | 604 | 1 | 398 | predicted protein [Populus trichocarpa] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
