y
Basic Information | |
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Species | Vitis vinifera |
Cazyme ID | GSVIVT01035880001 |
Family | GT47 |
Protein Properties | Length: 479 Molecular Weight: 54646.6 Isoelectric Point: 8.5616 |
Chromosome | Chromosome/Scaffold: 4 Start: 5206353 End: 5210218 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 146 | 430 | 0 |
EKRLKVYVYEEGEVPMIHDGPCKDIYTIEGRFIHEIEHGDGKFRTRDAERAHVYFMPFSVTWMVKYLYKPLTYNLTPLRQFVSDYVSVISTKYPFWNTTQ GADHFMLACHDWGPHASRGHPVLYNTSIRVLCNANTSEGFNPQKDVSLPEIHLYGGNVNPKLLSPPPPNSPRPFLAFFAGGLHGPIRPILIQHWMGRDTD LRVYEYLPKDMDYYSLMLQSKYCLCPSGHEVASPRIVEAIYSECVPVILSDHYVLPFSDVLRWEAFSVKVEASEIPRLKEVLQAI |
Full Sequence |
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Protein Sequence Length: 479 Download |
METNYGTLVS LLSCLCVASV VVVCIVSGHY SQSIKFSGAE PGDSVATIEL QTKVTASHEV 60 RAVFSSQPPA FYVNRLRNHT LIRKIKKRTR YQGQEEGLAR ARASIRKAFS NLNRSSEIGG 120 EDNNEVPTGD VYRNAGAFYQ SYVEMEKRLK VYVYEEGEVP MIHDGPCKDI YTIEGRFIHE 180 IEHGDGKFRT RDAERAHVYF MPFSVTWMVK YLYKPLTYNL TPLRQFVSDY VSVISTKYPF 240 WNTTQGADHF MLACHDWGPH ASRGHPVLYN TSIRVLCNAN TSEGFNPQKD VSLPEIHLYG 300 GNVNPKLLSP PPPNSPRPFL AFFAGGLHGP IRPILIQHWM GRDTDLRVYE YLPKDMDYYS 360 LMLQSKYCLC PSGHEVASPR IVEAIYSECV PVILSDHYVL PFSDVLRWEA FSVKVEASEI 420 PRLKEVLQAI SEEKYTRLKE GVRAVRRHFE LNQPAKRFDV FHMILHSVWL RRINLKLG* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-61 | 145 | 430 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 1 | 478 | 1 | 478 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 15 | 477 | 16 | 479 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 145 | 478 | 1 | 334 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 145 | 477 | 1 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 14 | 478 | 16 | 481 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |