| Basic Information | |
|---|---|
| Species | Vitis vinifera |
| Cazyme ID | GSVIVT01038114001 |
| Family | GH19 |
| Protein Properties | Length: 524 Molecular Weight: 56838.8 Isoelectric Point: 5.132 |
| Chromosome | Chromosome/Scaffold: 5 Start: 23559760 End: 23567531 |
| Description | homolog of carrot EP3-3 chitinase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 16 | 134 | 0 |
| VSDVVTEDFFNGIISQAAGSCAGKNFYSRNAFLNAASSYPQFGQDGSADDSKREIAAFFAHVAHETGHFCYIEEIDGASKDYCDESNTQYPCVAGKGYYG RGPLQISWNYNYGPAGQNL | |||
| GH19 | 324 | 523 | 0 |
| VEDVVTEDFFDGIINQVDASCTGKNFYTRRAFLDALNSYPEFGQGGYANDSKREIAAFFAHATHETGCFCYIEEIDGPSKNYCVEDTRYPCVPGKGYYGR GPLQITWNFNYGPAGESIGFNGSNNPEIVANDPVISFKTAFWFWMKNVHDIVNRGFSATIHAINGAECNGGNRDAVSARVEYYEDYCNQLGVFPGDNLPC | |||
| Full Sequence |
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| Protein Sequence Length: 524 Download |
| MTFVEKKSIE NSSVSVSDVV TEDFFNGIIS QAAGSCAGKN FYSRNAFLNA ASSYPQFGQD 60 GSADDSKREI AAFFAHVAHE TGHFCYIEEI DGASKDYCDE SNTQYPCVAG KGYYGRGPLQ 120 ISWNYNYGPA GQNLMHVKWY CRSNSFSCLI CHLFLSIGSD FLSKTICLLT VFFSLLLGDE 180 SLGETVANVL TSLPFIALGI QAPRKNLNCK LYANSLIGVG IASGLYHSSR GKLRKYLRWA 240 DYTMIATATV VNMVSKLVAI LIVGVLAGAL PWPVLAQNYS CNAGLCCSQF GFCGTGVRYC 300 GDGCQAGPCY SPPSGGGDGG CISVEDVVTE DFFDGIINQV DASCTGKNFY TRRAFLDALN 360 SYPEFGQGGY ANDSKREIAA FFAHATHETG CFCYIEEIDG PSKNYCVEDT RYPCVPGKGY 420 YGRGPLQITW NFNYGPAGES IGFNGSNNPE IVANDPVISF KTAFWFWMKN VHDIVNRGFS 480 ATIHAINGAE CNGGNRDAVS ARVEYYEDYC NQLGVFPGDN LPC* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00270 | ChtBD1 | 2.0e-7 | 276 | 307 | 32 | + Chitin binding domain. | ||
| pfam00182 | Glyco_hydro_19 | 1.0e-51 | 21 | 134 | 126 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 1.0e-54 | 21 | 134 | 125 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| pfam00182 | Glyco_hydro_19 | 6.0e-87 | 327 | 523 | 232 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 7.0e-95 | 328 | 523 | 230 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN76727.1 | 0 | 14 | 134 | 70 | 189 | hypothetical protein [Vitis vinifera] |
| EMBL | CAN76727.1 | 0 | 278 | 472 | 26 | 220 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI24653.1 | 0 | 1 | 523 | 1 | 523 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002273248.1 | 0 | 14 | 134 | 70 | 189 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002273248.1 | 0 | 253 | 523 | 1 | 271 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3hbh_A | 0 | 323 | 523 | 1 | 204 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3hbh_A | 1e-35 | 15 | 134 | 1 | 118 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3hbe_X | 0 | 323 | 523 | 1 | 204 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3hbe_X | 1e-35 | 15 | 134 | 1 | 118 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3hbd_A | 0 | 323 | 523 | 1 | 204 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FS958736 | 274 | 251 | 523 | 0 |
| FS958736 | 114 | 21 | 134 | 0 |
| EE075914 | 274 | 253 | 524 | 0 |
| EE075914 | 114 | 21 | 134 | 0 |
| EC973188 | 285 | 242 | 524 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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