y
Basic Information | |
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Species | Glycine max |
Cazyme ID | Glyma01g20460.1 |
Family | GH31 |
Protein Properties | Length: 929 Molecular Weight: 102942 Isoelectric Point: 6.6886 |
Chromosome | Chromosome/Scaffold: 01 Start: 24945684 End: 24950931 |
Description | alpha-xylosidase 1 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH31 | 278 | 769 | 0 |
FYFFSGPSPLNVVDQYTTLIGRPAPMPYWAFGFHQCRWGYHNLSVVEDVVENYKKAQIPLDVIWNDDDHMDGKKDFTLNPVNYPRPKLLNFLDKIHNIGM KYIVIIDPGIAVNTSYGVYQRGVANDVFIKYDGEPFLAQVWPGAVNFPDFLNPKTVSWWVDEIHRFHELVPVDGLWIDMNEVSNFCSGKCKIPKGKCPTG TGPGWICCLDCKNITKTRWDDPPYKINASGIKAPIGFKTIATSAYHYNGVLEYDAHSLYGFSQTIATHKGLQGLQGKRPFILSRSTYVGSGKYAAHWTGD NQGTWENLRYSISTMLNFGIFGVPMVGSDICGFYPQPTEELCNRWIEVGAFYPFSRDHANYYSPRQELYQWQSVAESARNALGIRYKLLPFLYTLNYEAH VSGAPIARPLFFSFPTYTECYGLSTQFLLGSSLMVSPVLEQGKTQVKALFPPGSWYSLLDWTHTITSKDGVYITLDAPLHVVNVHLYQNTIL |
Full Sequence |
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Protein Sequence Length: 929 Download |
MVSSNRFAAL PLCSLLLALL LCAVGASSSS SSSTNATKIG QGYRLVSIEE TPDGGLIGIL 60 QVKQKTKTYG PDIPLLRFYV KHETDNRLRV HITDAQKQRW EVPYNLLPRE QPPPLSQSIG 120 KSRKNPITVS QYSGSEFLFS YTSDPFSFAV KRKSNGETLF DSSSGDSDPF SSLVFKDQYL 180 EISTKLPKDA SLYGLGENTQ PHGIKLYPSD PYTLYTTDIS AINLNADLYG SHPVYMDLRN 240 AGGKASAHAV LLLNSNGMDV FYTGTSLTYK IIGGVFDFYF FSGPSPLNVV DQYTTLIGRP 300 APMPYWAFGF HQCRWGYHNL SVVEDVVENY KKAQIPLDVI WNDDDHMDGK KDFTLNPVNY 360 PRPKLLNFLD KIHNIGMKYI VIIDPGIAVN TSYGVYQRGV ANDVFIKYDG EPFLAQVWPG 420 AVNFPDFLNP KTVSWWVDEI HRFHELVPVD GLWIDMNEVS NFCSGKCKIP KGKCPTGTGP 480 GWICCLDCKN ITKTRWDDPP YKINASGIKA PIGFKTIATS AYHYNGVLEY DAHSLYGFSQ 540 TIATHKGLQG LQGKRPFILS RSTYVGSGKY AAHWTGDNQG TWENLRYSIS TMLNFGIFGV 600 PMVGSDICGF YPQPTEELCN RWIEVGAFYP FSRDHANYYS PRQELYQWQS VAESARNALG 660 IRYKLLPFLY TLNYEAHVSG APIARPLFFS FPTYTECYGL STQFLLGSSL MVSPVLEQGK 720 TQVKALFPPG SWYSLLDWTH TITSKDGVYI TLDAPLHVVN VHLYQNTILP MQQGGMVSKE 780 ARATPFTLIV TFPSDATQGE AKGNLFLDND ELPDMNLGNG YSTYVDLHAT VDQGAVKVWS 840 EVQEGKFALD KGWIIDSISV LGLEGSGAVS SLEIDGKPLM GGSNVNVTTS AHEHLNSEGE 900 GEKKTVMVAL RGLSIPVGKN FAMTWKMG* 960 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01055 | Glyco_hydro_31 | 6.0e-87 | 279 | 466 | 188 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. | ||
cd06602 | GH31_MGAM_SI_GAA | 4.0e-89 | 298 | 462 | 169 | + This family includes the following three closely related glycosyl hydrolase family 31 (GH31) enzymes: maltase-glucoamylase (MGAM), sucrase-isomaltase (SI), and lysosomal acid alpha-glucosidase (GAA), also known as acid-maltase. MGAM is one of the two enzymes responsible for catalyzing the last glucose-releasing step in starch digestion. SI is implicated in the digestion of dietary starch and major disaccharides such as sucrose and isomaltose, while GAA degrades glycogen in the lysosome, cleaving both alpha-1,4 and alpha-1,6 glucosidic linkages. MGAM and SI are anchored to small-intestinal brush-border epithelial cells. The absence of SI from the brush border membrane or its malfunction is associated with malabsorption disorders such as congenital sucrase-isomaltase deficiency (CSID). The domain architectures of MGAM and SI include two tandem GH31 catalytic domains, an N-terminal domain found near the membrane-bound end, and a C-terminal luminal domain. Both of the tandem GH31 domains of MGAM and SI are included in this family. The domain architecture of GAA includes an N-terminal TFF (trefoil factor family) domain in addition to the GH31 catalytic domain. Deficient GAA expression causes pompe disease, an autosomal recessive genetic disorder also known as glycogen storage disease type II (GSDII). | ||
cd06602 | GH31_MGAM_SI_GAA | 3.0e-92 | 530 | 698 | 170 | + This family includes the following three closely related glycosyl hydrolase family 31 (GH31) enzymes: maltase-glucoamylase (MGAM), sucrase-isomaltase (SI), and lysosomal acid alpha-glucosidase (GAA), also known as acid-maltase. MGAM is one of the two enzymes responsible for catalyzing the last glucose-releasing step in starch digestion. SI is implicated in the digestion of dietary starch and major disaccharides such as sucrose and isomaltose, while GAA degrades glycogen in the lysosome, cleaving both alpha-1,4 and alpha-1,6 glucosidic linkages. MGAM and SI are anchored to small-intestinal brush-border epithelial cells. The absence of SI from the brush border membrane or its malfunction is associated with malabsorption disorders such as congenital sucrase-isomaltase deficiency (CSID). The domain architectures of MGAM and SI include two tandem GH31 catalytic domains, an N-terminal domain found near the membrane-bound end, and a C-terminal luminal domain. Both of the tandem GH31 domains of MGAM and SI are included in this family. The domain architecture of GAA includes an N-terminal TFF (trefoil factor family) domain in addition to the GH31 catalytic domain. Deficient GAA expression causes pompe disease, an autosomal recessive genetic disorder also known as glycogen storage disease type II (GSDII). | ||
pfam01055 | Glyco_hydro_31 | 2.0e-109 | 523 | 769 | 251 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. | ||
cd06604 | GH31_glucosidase_II_MalA | 4.0e-119 | 298 | 680 | 389 | + Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized in Bacillus thermoamyloliquefaciens where it forms a homohexamer. This family also includes the MalA alpha-glucosidase from Sulfolobus sulfataricus and the AglA alpha-glucosidase from Picrophilus torridus. MalA is part of the carbohydrate-metabolizing machinery that allows this organism to utilize carbohydrates, such as maltose, as the sole carbon and energy source. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAA10382.2 | 0 | 25 | 928 | 27 | 934 | alpha-D-xylosidase [Tropaeolum majus] |
RefSeq | XP_002282429.1 | 0 | 15 | 928 | 7 | 921 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002311455.1 | 0 | 27 | 928 | 3 | 907 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002315944.1 | 0 | 31 | 928 | 24 | 925 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531635.1 | 0 | 12 | 928 | 8 | 927 | alpha-glucosidase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3w38_A | 0 | 13 | 864 | 14 | 852 | A Chain A, Spinosyn Rhamnosyltransferase Spng |
PDB | 3w37_A | 0 | 13 | 864 | 14 | 852 | A Chain A, Spinosyn Rhamnosyltransferase Spng |
PDB | 3lpp_D | 0 | 69 | 925 | 106 | 898 | A Chain A, Spinosyn Rhamnosyltransferase Spng |
PDB | 3lpp_C | 0 | 69 | 925 | 106 | 898 | A Chain A, Spinosyn Rhamnosyltransferase Spng |
PDB | 3lpp_B | 0 | 69 | 925 | 106 | 898 | A Chain A, Spinosyn Rhamnosyltransferase Spng |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
starch degradation I | RXN-2141 | EC-3.2.1.20 | α-glucosidase |