| Basic Information | |
|---|---|
| Species | Glycine max |
| Cazyme ID | Glyma07g00530.1 |
| Family | AA3 |
| Protein Properties | Length: 543 Molecular Weight: 58841.8 Isoelectric Point: 6.8391 |
| Chromosome | Chromosome/Scaffold: 07 Start: 253280 End: 255424 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 47 | 538 | 0 |
| SEDYYDYIVVGGGTAGCPLAATLSQSFRVLLLERGGVGHGDPNLMNQEGFLANLLNTESGDSPAQAFISEEGVPNARGRVLGGSSAINAGFYSRADADFF ARSGLPWNLTLVNDSYQWVEKEVVFRPNLKTWQSAVRDGLLEAGVTPYNGFTLDHAKGTKIGGSTFDGAGRRHTSADLLRYARASNIKVGVYASVERLLL AASSAIGVLYRDQEGDYHHAFLREQGEVILSAGAIGSPQLLLLSGIGPRPYLSSWGIPVAHHLPYVGHFLYDNPRNGITILPSLPLEHSLIQVVGITESG AYIEAASNVVPFTSPPHTALVLRSPLYLTVATIISKISGPVSSGFLRLASTEVKENPVVRFNYLNNQVDVERCVNGTRKIAEILRSRALRDFKFSNWFGE RDFRFIGPALPLHQSDFPSMADYCRRTVSTIWHYHGGCVVGRVVDPNLNLIGISSLRIVDGSVFSVSPGTNPQATLMMLGRYFGLKIIAERD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 543 Download |
| MERAISIVQL ECVTLLILSS TLFSCATQEQ GASSYLNMVV NASELPSEDY YDYIVVGGGT 60 AGCPLAATLS QSFRVLLLER GGVGHGDPNL MNQEGFLANL LNTESGDSPA QAFISEEGVP 120 NARGRVLGGS SAINAGFYSR ADADFFARSG LPWNLTLVND SYQWVEKEVV FRPNLKTWQS 180 AVRDGLLEAG VTPYNGFTLD HAKGTKIGGS TFDGAGRRHT SADLLRYARA SNIKVGVYAS 240 VERLLLAASS AIGVLYRDQE GDYHHAFLRE QGEVILSAGA IGSPQLLLLS GIGPRPYLSS 300 WGIPVAHHLP YVGHFLYDNP RNGITILPSL PLEHSLIQVV GITESGAYIE AASNVVPFTS 360 PPHTALVLRS PLYLTVATII SKISGPVSSG FLRLASTEVK ENPVVRFNYL NNQVDVERCV 420 NGTRKIAEIL RSRALRDFKF SNWFGERDFR FIGPALPLHQ SDFPSMADYC RRTVSTIWHY 480 HGGCVVGRVV DPNLNLIGIS SLRIVDGSVF SVSPGTNPQA TLMMLGRYFG LKIIAERDAN 540 NN* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK02106 | PRK02106 | 7.0e-34 | 216 | 526 | 364 | + choline dehydrogenase; Validated | ||
| TIGR01810 | betA | 1.0e-36 | 52 | 526 | 546 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| TIGR03970 | Rv0697 | 4.0e-38 | 52 | 526 | 524 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| COG2303 | BetA | 5.0e-45 | 51 | 539 | 556 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 30 | 537 | 556 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABE65766.1 | 0 | 35 | 537 | 38 | 550 | mandelonitrile lyase [Arabidopsis thaliana] |
| GenBank | ACN31582.1 | 0 | 29 | 537 | 31 | 582 | unknown [Zea mays] |
| RefSeq | NP_177448.1 | 0 | 35 | 537 | 38 | 550 | (R)-mandelonitrile lyase, putative / (R)-oxynitrilase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002277531.1 | 0 | 13 | 537 | 12 | 546 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311915.1 | 0 | 34 | 537 | 3 | 517 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1ju2_B | 0 | 26 | 541 | 2 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 1ju2_A | 0 | 26 | 541 | 2 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_B | 0 | 26 | 541 | 2 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_A | 0 | 26 | 541 | 2 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdn_B | 0 | 26 | 541 | 2 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| amygdalin and prunasin degradation | MANDELONITRILE-LYASE-RXN | EC-4.1.2.10 | (R)-mandelonitrile lyase |
| vicianin bioactivation | MANDELONITRILE-LYASE-RXN | EC-4.1.2.10 | (R)-mandelonitrile lyase |
