Basic Information | |
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Species | Glycine max |
Cazyme ID | Glyma08g12760.1 |
Family | GT20 |
Protein Properties | Length: 920 Molecular Weight: 103982 Isoelectric Point: 7.0513 |
Chromosome | Chromosome/Scaffold: 08 Start: 9339009 End: 9347103 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 80 | 549 | 0 |
TGKQRLLVVANRLPVSAVREGVESYRLDISVGGLVSALLGVKEFDTRWIGWAGVNVPDDVGQRALTKALAEMRCIPVFLDEEIVNQYYNGYCNNILWPLF HYLGLPQEDRLATTRTFQSQFDAYKKANQMFADVVNKHYEEGDVVWCHDYHLMFLPKCLKQYNDKMKVGWFLHTPFPSSEIHRTLPSRSELLRSVLAADL VGFHTYDYARHFVSACTRILGLEGTPEGVEDHGKLTRVAAFPIGIDSDRFTQALELPEVQEHMKELKERFAGRKVMLGVDRLDMIKGIPQKILAFEKFLE ENSHWRDKVVLLQIAVPTRKDVPEYQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHELCALYAVTDVALVTSLRDGMNLVSYEFVACQASKKGVL ILSEFAGAAQSLGAGAILVNPWNITEIAASIGYALEMSADEREKRHQFNFKHVKTHTSQEWAATFVSELN |
Full Sequence |
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Protein Sequence Length: 920 Download |
MPGNNFNCVP LTPRSRLERL LRERELRKSF KLVQPTEEAR DGSKEGEQFY GDSYISENEI 60 SGNHKEEEVT ETNADARGFT GKQRLLVVAN RLPVSAVREG VESYRLDISV GGLVSALLGV 120 KEFDTRWIGW AGVNVPDDVG QRALTKALAE MRCIPVFLDE EIVNQYYNGY CNNILWPLFH 180 YLGLPQEDRL ATTRTFQSQF DAYKKANQMF ADVVNKHYEE GDVVWCHDYH LMFLPKCLKQ 240 YNDKMKVGWF LHTPFPSSEI HRTLPSRSEL LRSVLAADLV GFHTYDYARH FVSACTRILG 300 LEGTPEGVED HGKLTRVAAF PIGIDSDRFT QALELPEVQE HMKELKERFA GRKVMLGVDR 360 LDMIKGIPQK ILAFEKFLEE NSHWRDKVVL LQIAVPTRKD VPEYQKLTSQ VHEIVGRING 420 RFGTLTAVPI HHLDRSLDFH ELCALYAVTD VALVTSLRDG MNLVSYEFVA CQASKKGVLI 480 LSEFAGAAQS LGAGAILVNP WNITEIAASI GYALEMSADE REKRHQFNFK HVKTHTSQEW 540 AATFVSELND TIVEAQLRTR QVPPLLPNKV AVDCYSKSNN RLIILGFNAT LNEPVDALGR 600 AGQIRELEHK LHSNTKEPLK KLSDDPKTTI VVLSGSGRAV LDKNFSEFNM WLAAENGIFL 660 RHTSSEWMTT MPENLNMDWV DSVKHVFEYF TERTPRSHFE LREMSIVWNY KYADVEFGRI 720 QARDLLQHLW AGPISNASLD VVQGGRSVEV RTIGVSKGAA IDRILGEIVH KKGMKTPIDY 780 VLCVGHFLAK DEDVYQFFEP ELPSESPPVP RAMLSKSNSY RPSSLSKLPA TTKTSSKAAQ 840 YKKQRSLSNI EKRELDQWRP MCGDKIALHE GSSVLDLKGD NYFSCVVGRK RSSARYLLKT 900 SDDVVNLLRD LAEHSSSPT* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03064 | PLN03064 | 0 | 1 | 917 | 935 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 75 | 919 | 845 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
TIGR02400 | trehalose_OtsA | 0 | 84 | 550 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
pfam00982 | Glyco_transf_20 | 0 | 83 | 550 | 474 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 0 | 84 | 765 | 689 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_177979.1 | 0 | 1 | 918 | 1 | 942 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002305707.1 | 0 | 21 | 918 | 1 | 898 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002331300.1 | 0 | 1 | 916 | 1 | 922 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522296.1 | 0 | 1 | 916 | 1 | 913 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
RefSeq | XP_002531237.1 | 0 | 1 | 916 | 1 | 924 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 84 | 560 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 84 | 560 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 84 | 560 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 84 | 560 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1uqu_B | 0 | 84 | 560 | 3 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DW069910 | 288 | 170 | 457 | 0 |
CX546763 | 299 | 75 | 373 | 0 |
CV711307 | 293 | 82 | 374 | 0 |
ES813375 | 355 | 445 | 798 | 0 |
CB651133 | 280 | 111 | 390 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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