| Basic Information | |
|---|---|
| Species | Glycine max |
| Cazyme ID | Glyma10g11720.3 |
| Family | GH89 |
| Protein Properties | Length: 808 Molecular Weight: 92414.7 Isoelectric Point: 7.268 |
| Chromosome | Chromosome/Scaffold: 10 Start: 12054324 End: 12096017 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH89 | 92 | 798 | 0 |
| PEIIIRGTTAVEIASGLHWYLKYWCGAHVSWDKTGGIQTTSIPEPGSLPSLKDEGLKIKRPVPWNYYQNVVTSSYSYVWWNWERWEKELDWMALQGVNLP LAFTGQEAIWQKVFKDFNISSKDLNNFFGGPAFLAWARMGNLHGWGGPLSQNWLDQQLVLQKQIISRMLELGMTPVLPSFSGNVPAALTKIFPSAKITRL GDWNTVDGDPRWCCTYLLDPSDPLFVEIGEAFIRKQIKEYGDVTDIYNCDTFNENSPPTNDPEYISNLGAAVYKGISKGDKDAVWLMQGWLFYSDSSFWK PPQMKALLHSVPFGKMIVLDLFADVKPIWKNSFQFYGTPYIWCMLHNFGGNIEMYGTLDSISSGPVDARVSANSTMVGVGMCMEGIEQNPIVYELMSEMA FRDKKVKVSEWIKSYCHRRYGKVIHQVESAWEILYHTIYNCTDGIADHNHDFIVMFPDWNPSTNSVTGTSNNQKIYLLPPGNRRYLFQETLSDMPQAHLW YPSDDVIKALQLFLAGGKNLAGSLTYRYDLVDLTRQVLSKLANQVYHKAVTSYQKKNIEALQFHSNKFLQLIKDIDVLLASDDNFLLGTWLESAKKLAVN PSEIKQYEWNARTQVTMWFDTNETTQSKLHDYANKFWSGLLESYYLPRASTYFSHLTESLRQNDKFKLIEWRKQWISQSNKWQEGNELYPVKAKGDALTI SQALYEK | |||
| Full Sequence |
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| Protein Sequence Length: 808 Download |
| MLKLGFVFLI LILTPLLPAA LSKYEAIEPL LQRLDSKRAP PSVQEAAAIG LLKRLLPIHF 60 SSFQFKIVSK DVCGGDSCFL INNHNKSSQN EPEIIIRGTT AVEIASGLHW YLKYWCGAHV 120 SWDKTGGIQT TSIPEPGSLP SLKDEGLKIK RPVPWNYYQN VVTSSYSYVW WNWERWEKEL 180 DWMALQGVNL PLAFTGQEAI WQKVFKDFNI SSKDLNNFFG GPAFLAWARM GNLHGWGGPL 240 SQNWLDQQLV LQKQIISRML ELGMTPVLPS FSGNVPAALT KIFPSAKITR LGDWNTVDGD 300 PRWCCTYLLD PSDPLFVEIG EAFIRKQIKE YGDVTDIYNC DTFNENSPPT NDPEYISNLG 360 AAVYKGISKG DKDAVWLMQG WLFYSDSSFW KPPQMKALLH SVPFGKMIVL DLFADVKPIW 420 KNSFQFYGTP YIWCMLHNFG GNIEMYGTLD SISSGPVDAR VSANSTMVGV GMCMEGIEQN 480 PIVYELMSEM AFRDKKVKVS EWIKSYCHRR YGKVIHQVES AWEILYHTIY NCTDGIADHN 540 HDFIVMFPDW NPSTNSVTGT SNNQKIYLLP PGNRRYLFQE TLSDMPQAHL WYPSDDVIKA 600 LQLFLAGGKN LAGSLTYRYD LVDLTRQVLS KLANQVYHKA VTSYQKKNIE ALQFHSNKFL 660 QLIKDIDVLL ASDDNFLLGT WLESAKKLAV NPSEIKQYEW NARTQVTMWF DTNETTQSKL 720 HDYANKFWSG LLESYYLPRA STYFSHLTES LRQNDKFKLI EWRKQWISQS NKWQEGNELY 780 PVKAKGDALT ISQALYEKYF QNKLINH* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12971 | NAGLU_N | 2.0e-21 | 44 | 136 | 93 | + Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This N-terminal domain has an alpha-beta fold. | ||
| pfam12972 | NAGLU_C | 3.0e-105 | 501 | 799 | 299 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| pfam05089 | NAGLU | 0 | 157 | 493 | 337 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI24942.1 | 0 | 6 | 800 | 69 | 867 | unnamed protein product [Vitis vinifera] |
| GenBank | EEC75285.1 | 0 | 39 | 801 | 51 | 812 | hypothetical protein OsI_11626 [Oryza sativa Indica Group] |
| RefSeq | NP_196873.1 | 0 | 24 | 800 | 25 | 805 | alpha-N-acetylglucosaminidase family / NAGLU family [Arabidopsis thaliana] |
| RefSeq | XP_002273084.1 | 0 | 6 | 800 | 4 | 802 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314048.1 | 0 | 20 | 800 | 22 | 805 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 0 | 51 | 789 | 177 | 866 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
| PDB | 2vcb_A | 0 | 51 | 789 | 177 | 866 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
| PDB | 2vca_A | 0 | 51 | 789 | 177 | 866 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
| PDB | 2vc9_A | 0 | 51 | 789 | 177 | 866 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 0 | 51 | 789 | 200 | 889 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
