| Basic Information | |
|---|---|
| Species | Glycine max |
| Cazyme ID | Glyma10g15910.1 |
| Family | CE1 |
| Protein Properties | Length: 285 Molecular Weight: 31955.1 Isoelectric Point: 7.3392 |
| Chromosome | Chromosome/Scaffold: 10 Start: 18699186 End: 18719524 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 25 | 281 | 0 |
| SPTLGCSMNFHIYFPRSPSPSHKFPVLYFLSGLTCTDENFIFKSGAQRAASAEGVALVAPDTSPRGLNVEGEADSWDLGAGAGFYLNATQEKWKNWRMYD YVVKELPKLLSDNFPHLETSKASIFGHSMGGHGALTIYLKNQDKYKSVSAFAPIANPINCPWGQKAFSNYLGDNKSDWEDYDATCLVTKFPNVSSTILID QGEDDKFLPDQLLPHKFEQACKKANVPLLLRFQPGYDHLYYFIATFIDDHIRHHAQA | |||
| Full Sequence |
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| Protein Sequence Length: 285 Download |
| METKPTEISS GKMFGGYNKR FRHFSPTLGC SMNFHIYFPR SPSPSHKFPV LYFLSGLTCT 60 DENFIFKSGA QRAASAEGVA LVAPDTSPRG LNVEGEADSW DLGAGAGFYL NATQEKWKNW 120 RMYDYVVKEL PKLLSDNFPH LETSKASIFG HSMGGHGALT IYLKNQDKYK SVSAFAPIAN 180 PINCPWGQKA FSNYLGDNKS DWEDYDATCL VTKFPNVSST ILIDQGEDDK FLPDQLLPHK 240 FEQACKKANV PLLLRFQPGY DHLYYFIATF IDDHIRHHAQ ALKS* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1506 | DAP2 | 2.0e-5 | 20 | 278 | 284 | + Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism] | ||
| pfam00756 | Esterase | 4.0e-53 | 25 | 277 | 265 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 2.0e-84 | 1 | 283 | 312 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 4.0e-132 | 8 | 282 | 276 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 1 | 284 | 284 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0006508 | proteolysis |
| GO:0008236 | serine-type peptidase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0018738 | S-formylglutathione hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACJ11734.1 | 0 | 1 | 283 | 1 | 283 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| GenBank | ACJ84789.1 | 0 | 6 | 282 | 7 | 282 | unknown [Medicago truncatula] |
| GenBank | ACU18661.1 | 0 | 1 | 251 | 1 | 251 | unknown [Glycine max] |
| GenBank | ACU19052.1 | 0 | 1 | 283 | 1 | 283 | unknown [Glycine max] |
| RefSeq | XP_002284489.1 | 0 | 1 | 282 | 1 | 282 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 7 | 284 | 5 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 7 | 284 | 5 | 282 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 8 | 284 | 7 | 280 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 8 | 284 | 7 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 8 | 284 | 7 | 280 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formaldehyde oxidation II (glutathione-dependent) | S-FORMYLGLUTATHIONE-HYDROLASE-RXN | EC-3.1.2.12 | S-formylglutathione hydrolase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| HO795182 | 282 | 1 | 282 | 0 |
| FF388001 | 280 | 1 | 280 | 0 |
| HO777747 | 281 | 2 | 282 | 0 |
| FD794726 | 265 | 3 | 267 | 0 |
| DV157903 | 282 | 1 | 282 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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