| Basic Information | |
|---|---|
| Species | Glycine max |
| Cazyme ID | Glyma13g39750.2 |
| Family | GH29 |
| Protein Properties | Length: 536 Molecular Weight: 60388.6 Isoelectric Point: 5.5919 |
| Chromosome | Chromosome/Scaffold: 13 Start: 40269548 End: 40272890 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH29 | 66 | 359 | 0 |
| QWQLDGMALFFHFGTNTFTDSEWGTGHANPTVFNPTKLNASQWIRVAKDSGFSRVILTVKHHDGFCLWPSDYTNYTVRSSNWRNGNGDVVAELAAAAKDA GVGLGFYLSPWDRHEACYGDTLQYNEFYLAQMTELLTRYGEVKDIFLDAAKEDETDMHYLFDSWFSLIHQLQPGAIVFSDLGPDTRWAGNEYGAAGSTCW SLYNKTGYEIGYIDNQYNSEGDQFGPDWLPATCDVSIRTGWFWHASEQPKSARSLLEIYYKSVGRNCQLLLNVPPNSSGLISDEDIQVLQEFAE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 536 Download |
| MKLNSKSLRL SCKSHNPGIK ISTCTLPNFL IRILLLCLCC FLVPASCSRK PPPLPILPLP 60 TTFQLQWQLD GMALFFHFGT NTFTDSEWGT GHANPTVFNP TKLNASQWIR VAKDSGFSRV 120 ILTVKHHDGF CLWPSDYTNY TVRSSNWRNG NGDVVAELAA AAKDAGVGLG FYLSPWDRHE 180 ACYGDTLQYN EFYLAQMTEL LTRYGEVKDI FLDAAKEDET DMHYLFDSWF SLIHQLQPGA 240 IVFSDLGPDT RWAGNEYGAA GSTCWSLYNK TGYEIGYIDN QYNSEGDQFG PDWLPATCDV 300 SIRTGWFWHA SEQPKSARSL LEIYYKSVGR NCQLLLNVPP NSSGLISDED IQVLQEFAEL 360 KRSIFSHNLA INAVINASSI RGGIQETHFS PYNVLEEGIY TYWAPWENQS KWILYIDLQE 420 LVSFNVLQLQ EPINMGQRVI EFHLEALSPD GVWMRVVNGT TIGYQRLLLF PKLKAQYLKL 480 VMDKSRADPL ISYFGIYMDP VTILSDISDK KSGACFNGSQ VLQTTTNNSY PSATM* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00754 | F5_F8_type_C | 0.001 | 375 | 487 | 121 | + F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. | ||
| pfam01120 | Alpha_L_fucos | 9.0e-23 | 98 | 359 | 284 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 1.0e-23 | 98 | 359 | 283 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 3.0e-53 | 64 | 497 | 451 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_180377.2 | 0 | 50 | 526 | 28 | 496 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
| Swiss-Prot | Q8GW72 | 0 | 50 | 526 | 28 | 496 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
| RefSeq | XP_002276131.1 | 0 | 14 | 520 | 5 | 509 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313533.1 | 0 | 61 | 499 | 15 | 454 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523703.1 | 0 | 64 | 506 | 67 | 511 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ues_B | 0 | 60 | 492 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 60 | 492 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 60 | 492 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 60 | 492 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3uet_B | 0 | 60 | 492 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
 | ||||
| Hit | Length | Start | End | EValue |
| CX711036 | 272 | 265 | 536 | 0 |
| FK016895 | 258 | 279 | 536 | 0 |
| CX708016 | 240 | 297 | 536 | 0 |
| CX701129 | 229 | 308 | 536 | 0 |
| CX701129 | 38 | 270 | 307 | 0.0000000000003 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
