| Basic Information | |
|---|---|
| Species | Glycine max |
| Cazyme ID | Glyma17g14130.1 |
| Family | AA3 |
| Protein Properties | Length: 582 Molecular Weight: 62965.7 Isoelectric Point: 6.84 |
| Chromosome | Chromosome/Scaffold: 17 Start: 10893292 End: 10898766 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 39 | 568 | 0 |
| TAPDVSYYDYIVIGGGTAGCPLAATLSQNYSVLLLERGGSPYGNPNISDLAAFGAALSDTSPTSPAQRFISEDGVINSRARVLGGGSCLNAGFYTRASPQ YVREAGWDGRAVNESYEWVEKIVAFEPQLKQWQSAVRDGLIEIGVVPNNGFTYDHIDGTKVGGTIFDQNGFRHTAADLLEYAKPTGITVLLDATVHRILF RVKEGSKPTAHGVVFRDSLGGRHKVYLKADPRNEIIVSAGALGSPQLLMLSGIGPREHLKAHNIRITLNQPLVGQGMTDNPMNAIFVPSPVPVEVSLIEV VGITSFGSYIEAASGENFAGGSPKDYGMFSPKIGQLSTVPPKERTPEALAKATELMETLEQAAFRGGFILEKIMGPISSGHLELRTRDPNDNPSVTFNYF QDPRDLQRCVQGLSTVEKIIESKAFSPFRYPNMPVPVLLNLTASAPVNLLPKHTNSSLSLEQYCRDTVMTIWHYHGGCQVGKVLDRDYKLLGVDALRVID GSTFNYSPGTNPQATVMMLGRYMGVKILSE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 582 Download |
| MGVLWWKLFF AALAGILFST QHCASQKVPN YTFMHNATTA PDVSYYDYIV IGGGTAGCPL 60 AATLSQNYSV LLLERGGSPY GNPNISDLAA FGAALSDTSP TSPAQRFISE DGVINSRARV 120 LGGGSCLNAG FYTRASPQYV REAGWDGRAV NESYEWVEKI VAFEPQLKQW QSAVRDGLIE 180 IGVVPNNGFT YDHIDGTKVG GTIFDQNGFR HTAADLLEYA KPTGITVLLD ATVHRILFRV 240 KEGSKPTAHG VVFRDSLGGR HKVYLKADPR NEIIVSAGAL GSPQLLMLSG IGPREHLKAH 300 NIRITLNQPL VGQGMTDNPM NAIFVPSPVP VEVSLIEVVG ITSFGSYIEA ASGENFAGGS 360 PKDYGMFSPK IGQLSTVPPK ERTPEALAKA TELMETLEQA AFRGGFILEK IMGPISSGHL 420 ELRTRDPNDN PSVTFNYFQD PRDLQRCVQG LSTVEKIIES KAFSPFRYPN MPVPVLLNLT 480 ASAPVNLLPK HTNSSLSLEQ YCRDTVMTIW HYHGGCQVGK VLDRDYKLLG VDALRVIDGS 540 TFNYSPGTNP QATVMMLGRY MGVKILSERL GGAAAAAETE Q* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01810 | betA | 4.0e-21 | 47 | 318 | 302 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| pfam05199 | GMC_oxred_C | 4.0e-26 | 414 | 558 | 150 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR03970 | Rv0697 | 2.0e-35 | 47 | 558 | 558 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| COG2303 | BetA | 9.0e-46 | 46 | 569 | 564 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 8 | 570 | 579 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI34759.1 | 0 | 23 | 570 | 24 | 572 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001053612.1 | 0 | 30 | 571 | 33 | 582 | Os04g0573100 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002282510.1 | 0 | 34 | 570 | 1 | 538 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002298074.1 | 0 | 1 | 570 | 1 | 570 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509694.1 | 0 | 3 | 570 | 6 | 542 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 32 | 569 | 13 | 517 | G Chain G, Human G Protein-Coupled Receptor Kinase 2 In Complex With Soluble Gbetagamma Subunits And Paroxetine |
| PDB | 3gdp_A | 0 | 32 | 569 | 13 | 517 | G Chain G, Human G Protein-Coupled Receptor Kinase 2 In Complex With Soluble Gbetagamma Subunits And Paroxetine |
| PDB | 3gdn_B | 0 | 32 | 569 | 13 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 32 | 569 | 13 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 32 | 569 | 13 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
| cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
| suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
