Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.002G184100.1 |
Family | GT47 |
Protein Properties | Length: 433 Molecular Weight: 49949.4 Isoelectric Point: 9.0174 |
Chromosome | Chromosome/Scaffold: 02 Start: 48851438 End: 48854982 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 52 | 366 | 0 |
LRVYMYDLPRKFHVGMMDRRSFEGPAPVTADNLPPWPSNSGIKKQHSVEYWLMASLLYGGNGNEDREAVRVSDPESAEAFFVPFFSSLSFNTHGHNMTDP ETEVDRRLQVELLEFLQKSKYYQRSGGRDHVIPMTHPNAFRFLRQELNASILIVVDFGRYPKTMSSLSKDVVAPYVHVVDSFTDDDALDPYESRTTLLFF RGNTVRKDQGKIRIKLAKILSGIDDVHYEKSVATPKNIIMSTEGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDKIELPYEDEIDYSEFSIFFSM KEALEPGYLVNQLRQ |
Full Sequence |
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Protein Sequence Length: 433 Download |
MYGKAAICLS FVILFLISCS IYVGTVDLRS YFFPLLQSPQ VPRSLCASGP PLRVYMYDLP 60 RKFHVGMMDR RSFEGPAPVT ADNLPPWPSN SGIKKQHSVE YWLMASLLYG GNGNEDREAV 120 RVSDPESAEA FFVPFFSSLS FNTHGHNMTD PETEVDRRLQ VELLEFLQKS KYYQRSGGRD 180 HVIPMTHPNA FRFLRQELNA SILIVVDFGR YPKTMSSLSK DVVAPYVHVV DSFTDDDALD 240 PYESRTTLLF FRGNTVRKDQ GKIRIKLAKI LSGIDDVHYE KSVATPKNII MSTEGMRSSK 300 FCLHPAGDTP SSCRLFDAIV SHCVPVIVSD KIELPYEDEI DYSEFSIFFS MKEALEPGYL 360 VNQLRQFPKD RWVEMWKQLK NISHHFEFQY PPKKEDGVNM LWRQVKRKLP RAQLAIHRSR 420 RLKVPDWWQR RR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-73 | 48 | 367 | 328 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC18793.1 | 0 | 1 | 409 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
RefSeq | NP_176908.2 | 0 | 1 | 428 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 27 | 432 | 27 | 430 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 51 | 428 | 1 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512333.1 | 0 | 1 | 431 | 1 | 434 | catalytic, putative [Ricinus communis] |