| Basic Information | |
|---|---|
| Species | Gossypium raimondii |
| Cazyme ID | Gorai.002G227600.1 |
| Family | CE1 |
| Protein Properties | Length: 284 Molecular Weight: 31735 Isoelectric Point: 7.3392 |
| Chromosome | Chromosome/Scaffold: 02 Start: 58625871 End: 58631834 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 25 | 280 | 0 |
| SPTLGCSMTFHIYFPPSSSPSHKFPILYWLSGLTCTDENFIIKSGAQRAASAEGVALIAPDTSPRGLNVEGEADSWDFGVGAGFYLNATQQKWKNWRMYD YVVKELPKLLSENFPQLDTSKASISGHSMGGHGALTIYLKNLDKYKSASAFAPIANPINCPWGQKAFTNYLGNDKAAWEEYDATCLIKKFHNVSATILID QGEDDKFLDQLLAHKFEEACRSVNVPLLLRLQPGYDHSYFFISTFIDDHIRHHAQA | |||
| Full Sequence |
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| Protein Sequence Length: 284 Download |
| METKPTEIGS SKMFGGYNKR YKHFSPTLGC SMTFHIYFPP SSSPSHKFPI LYWLSGLTCT 60 DENFIIKSGA QRAASAEGVA LIAPDTSPRG LNVEGEADSW DFGVGAGFYL NATQQKWKNW 120 RMYDYVVKEL PKLLSENFPQ LDTSKASISG HSMGGHGALT IYLKNLDKYK SASAFAPIAN 180 PINCPWGQKA FTNYLGNDKA AWEEYDATCL IKKFHNVSAT ILIDQGEDDK FLDQLLAHKF 240 EEACRSVNVP LLLRLQPGYD HSYFFISTFI DDHIRHHAQA LKL* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01738 | DLH | 0.0002 | 138 | 264 | 127 | + Dienelactone hydrolase family. | ||
| pfam00756 | Esterase | 7.0e-52 | 25 | 276 | 265 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 2.0e-82 | 1 | 283 | 313 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 1.0e-130 | 8 | 281 | 276 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 1 | 283 | 284 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0006508 | proteolysis |
| GO:0008236 | serine-type peptidase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACJ11734.1 | 0 | 1 | 283 | 1 | 284 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| GenBank | ACU19052.1 | 0 | 1 | 283 | 1 | 284 | unknown [Glycine max] |
| RefSeq | NP_181684.1 | 0 | 1 | 283 | 1 | 284 | SFGH (S-FORMYLGLUTATHIONE HYDROLASE); S-formylglutathione hydrolase/ hydrolase, acting on ester bonds [Arabidopsis thaliana] |
| RefSeq | XP_002284489.1 | 0 | 1 | 283 | 1 | 284 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002308013.1 | 0 | 1 | 283 | 1 | 284 | esterase d, s-formylglutathione hydrolase [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 7 | 281 | 5 | 280 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 7 | 281 | 5 | 280 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 8 | 282 | 7 | 279 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 8 | 282 | 7 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 8 | 282 | 7 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| ES839491 | 284 | 1 | 284 | 0 |
| DT549152 | 283 | 1 | 282 | 0 |
| ES807790 | 285 | 1 | 284 | 0 |
| ES841762 | 280 | 1 | 279 | 0 |
| ES828179 | 282 | 1 | 281 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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