Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.003G036900.1 |
Family | GT47 |
Protein Properties | Length: 436 Molecular Weight: 50067.3 Isoelectric Point: 8.8349 |
Chromosome | Chromosome/Scaffold: 03 Start: 3891431 End: 3894542 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 111 | 388 | 0 |
EKKFKIYIYPDGDPKTFYQTPRKLTGKYASEGYFFQNIRESRFRTEDPDQAHLFFIPISCHKMRGKGTSYENMTIIVQNYLDGLIAKYPYWNRTLGADHF FVTCHDVGVRATEGVPFLVKNAIRVVCSPSYDVGFIPHKDVALPQVLQPFALPAGGNDVENRTSLGFWAGHRNSKIRVILARVWENDTELDISNNRISRA TGHLVYQKRFYRTKFCICPGGSQVNSARITDSIHYGCVPVILSNYYDLPFNDILDWQKFAVILRESDVYQLKQILKSI |
Full Sequence |
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Protein Sequence Length: 436 Download |
MIAGKPPLQQ SQLFSLKGSV LTLSILTLIS FTYFSFKSLR PPLPFSPPTP QITLLPSSAT 60 GTNTTTPSQP RIVAEKKEGN VGEEQEDNDD DFFTDIYHSP KLFKLNFEEM EKKFKIYIYP 120 DGDPKTFYQT PRKLTGKYAS EGYFFQNIRE SRFRTEDPDQ AHLFFIPISC HKMRGKGTSY 180 ENMTIIVQNY LDGLIAKYPY WNRTLGADHF FVTCHDVGVR ATEGVPFLVK NAIRVVCSPS 240 YDVGFIPHKD VALPQVLQPF ALPAGGNDVE NRTSLGFWAG HRNSKIRVIL ARVWENDTEL 300 DISNNRISRA TGHLVYQKRF YRTKFCICPG GSQVNSARIT DSIHYGCVPV ILSNYYDLPF 360 NDILDWQKFA VILRESDVYQ LKQILKSISH EEFVSLHNNL VKVQKHFQWN TPPVKFDAFH 420 MVIYELWLRH HVIKY* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-58 | 110 | 388 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 1 | 435 | 1 | 409 | unknown [Glycine max] |
RefSeq | NP_195517.1 | 0 | 10 | 435 | 16 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 1 | 435 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 13 | 435 | 1 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 87 | 435 | 58 | 406 | catalytic, putative [Ricinus communis] |