Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.004G103500.3 |
Family | GT20 |
Protein Properties | Length: 656 Molecular Weight: 75155 Isoelectric Point: 6.7342 |
Chromosome | Chromosome/Scaffold: 04 Start: 19825924 End: 19828845 |
Description | trehalose phosphatase/synthase 11 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 43 | 537 | 0 |
AMPRKRVIIVSNQLPLRAWRDSVSNEWCFEFDENDLLALLRDAFPPDTEVRYVGTLKADVDTADQEEVAQVLHDKFSCETIFLPVDMRNEFYHGFCKHYL WPLFHYMMPMTGNDGGRFDRSQWMAYVSANRIFADKVLEVTDRDDEDEDHVWVHDYHLMALPTFLRRRSNRVKLGFFLHSPFPSSDMYKTLPVRDEILRA LLNCDLIGFHTFDYARHFLSSCRRILGLHSESNRGHIALEYYGRTVTIKILPAGIHMGQLESMMSEESTLRMAKELKHKYEGKIMMVGVDDLDLFKGIPQ KFSAMGELLETNQELRGKVVLVQITNPARSLGRDVQQLLDEANSIAKEVNNKYGEPGYQPIVFLKGPVTTQEKLAYYAVAEFCVVTPVRDGMNLVPYKYT VCRQGCPALDRALGVDENSPPKNSVIIVSEFIGCSPSLSGAIRVNPWNIDEMANAMYRAIDLSETEKHLRHEKHYKYISSHDVAYWARSFDQDLV |
Full Sequence |
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Protein Sequence Length: 656 Download |
MVSSCCLDQL NLLSTDDFRV MNRIPRVMKV SGVISDFGED QQAMPRKRVI IVSNQLPLRA 60 WRDSVSNEWC FEFDENDLLA LLRDAFPPDT EVRYVGTLKA DVDTADQEEV AQVLHDKFSC 120 ETIFLPVDMR NEFYHGFCKH YLWPLFHYMM PMTGNDGGRF DRSQWMAYVS ANRIFADKVL 180 EVTDRDDEDE DHVWVHDYHL MALPTFLRRR SNRVKLGFFL HSPFPSSDMY KTLPVRDEIL 240 RALLNCDLIG FHTFDYARHF LSSCRRILGL HSESNRGHIA LEYYGRTVTI KILPAGIHMG 300 QLESMMSEES TLRMAKELKH KYEGKIMMVG VDDLDLFKGI PQKFSAMGEL LETNQELRGK 360 VVLVQITNPA RSLGRDVQQL LDEANSIAKE VNNKYGEPGY QPIVFLKGPV TTQEKLAYYA 420 VAEFCVVTPV RDGMNLVPYK YTVCRQGCPA LDRALGVDEN SPPKNSVIIV SEFIGCSPSL 480 SGAIRVNPWN IDEMANAMYR AIDLSETEKH LRHEKHYKYI SSHDVAYWAR SFDQDLVRAC 540 RDHYHKRYWR VGLGLAFRLV ALEPNFRKLL GDTLNSAYKI TSSRLILLDY DGTMMPPTSV 600 NKGPSHEVIS VLNRLCDDPK NIVFIVSGRD RDTLSKWFSS CEKLGIAAEH GYFTR* 660 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR02400 | trehalose_OtsA | 8.0e-127 | 48 | 538 | 492 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
PRK14501 | PRK14501 | 4.0e-127 | 47 | 655 | 613 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
cd03788 | GT1_TPS | 3.0e-175 | 48 | 536 | 489 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
PLN02205 | PLN02205 | 0 | 1 | 655 | 672 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 47 | 538 | 496 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX16014.1 | 0 | 13 | 655 | 12 | 663 | trehalose-6-phosphate synthase [Ginkgo biloba] |
RefSeq | NP_179460.1 | 0 | 8 | 655 | 8 | 655 | ATTPS11; transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002308438.1 | 0 | 1 | 655 | 1 | 660 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002325087.1 | 0 | 12 | 655 | 1 | 642 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533178.1 | 0 | 48 | 655 | 8 | 612 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 131 | 536 | 73 | 450 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 131 | 536 | 73 | 450 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 131 | 536 | 73 | 450 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 131 | 536 | 73 | 450 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 131 | 536 | 74 | 451 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 603 | 58 | 655 | 0 |
HO779327 | 517 | 89 | 605 | 0 |
DW486206 | 240 | 238 | 477 | 0 |
DW486207 | 240 | 238 | 477 | 0 |
HO779327 | 55 | 601 | 655 | 0.000000000000004 |
Sequence Alignments (This image is cropped. Click for full image.) |
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