| Basic Information | |
|---|---|
| Species | Gossypium raimondii |
| Cazyme ID | Gorai.004G113300.1 |
| Family | GT47 |
| Protein Properties | Length: 498 Molecular Weight: 56611.5 Isoelectric Point: 9.6915 |
| Chromosome | Chromosome/Scaffold: 04 Start: 26047604 End: 26051765 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 117 | 435 | 0 |
| LLRVYMYDLPSEFHFGLLGWKGKLNQVWPEVNDPSRIPSYPGGLNLQHSIEYWLTLDLLSSNTPNVVRPCAAIRVTNSSQADIIFVPFFASLSYNRHSKL RGKEKVSVNKMLQNKLVKFLTAQNEWKRFGGKDHVIVAHHPNSMLDARGKLGSAMFVLADFGRYPSEIANIEKDIIAPYRHVVRTIPSADSAPFDKRPIL VFFQGAIYRKDGGAIRQELYYLLKDEKDVHFTFGTIQGNGVNQAGHGMASSKFCLNIAGDTPSSNRLFDAIVSHCVPVIVSDEIELPFEDVIDYSEICIF VRASDAVKKGYLLNLLRGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 498 Download |
| MLSMSEKGIF PSRFLFCIIT ISMFLLILSS VFLLQFGNSS LIPHSVFKLI LVNGTVYLKS 60 NVKNELKLPF FSSESSKVDA QKLVRSGDSS CHKSGYRKKM CAYRHPTIES CDTNQALLRV 120 YMYDLPSEFH FGLLGWKGKL NQVWPEVNDP SRIPSYPGGL NLQHSIEYWL TLDLLSSNTP 180 NVVRPCAAIR VTNSSQADII FVPFFASLSY NRHSKLRGKE KVSVNKMLQN KLVKFLTAQN 240 EWKRFGGKDH VIVAHHPNSM LDARGKLGSA MFVLADFGRY PSEIANIEKD IIAPYRHVVR 300 TIPSADSAPF DKRPILVFFQ GAIYRKDGGA IRQELYYLLK DEKDVHFTFG TIQGNGVNQA 360 GHGMASSKFC LNIAGDTPSS NRLFDAIVSH CVPVIVSDEI ELPFEDVIDY SEICIFVRAS 420 DAVKKGYLLN LLRGISRDQW TKMWEKLKET VRHFQYQYPS QLCDAVDMIW EAVARKVPMV 480 QLKTHRENRY RRSERIK* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-55 | 118 | 435 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_565089.1 | 0 | 1 | 494 | 1 | 453 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002284930.1 | 0 | 4 | 494 | 1 | 449 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002284932.1 | 0 | 88 | 494 | 4 | 410 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
| RefSeq | XP_002320639.1 | 0 | 118 | 492 | 3 | 374 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002514760.1 | 0 | 4 | 494 | 1 | 488 | catalytic, putative [Ricinus communis] |
