| Basic Information | |
|---|---|
| Species | Gossypium raimondii |
| Cazyme ID | Gorai.004G170700.4 |
| Family | GH89 |
| Protein Properties | Length: 622 Molecular Weight: 70989.4 Isoelectric Point: 7.6079 |
| Chromosome | Chromosome/Scaffold: 04 Start: 47026387 End: 47032809 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH89 | 1 | 617 | 0 |
| MALQGINLPLAFSGQEAIWQKVFMGFNISMEDLNDFFGGPAFLAWARMGNLHTWGGPLSKNWLKQQLVLQKKILSRMVELGMTPVLPSFSGNVPAALKTI FPTANITRLGDWNTVDGDPHWCCTYLLNPSDPLFVEIGEAFIKMQIKEYGDVTDIYNCDTFNENSPPTNDTIYISSLGAAVYKAMSNGDKDAVWLMQGWL FYSDSTFWKPPQMKALLHSVPVGKMIVLDLFADVKPIWATSSQFYGTPYVWCLLHNFGGNIEMYGTLDAISSGPVDARISKNSTMVGVGMCMEGIEQNPV VYELMSEMAFRKEKVQVLEWLKTYTHRRYGKSVQQIKEAWAILYHTVYNCTDGIADHNIDFIVKFPDWDPSINFGSRPSKLNSMHTFRLRTRSRRFSFQE RSSDLPQAHLWYSTHEVVSALKLFLAAGNDLAGSLTYRYDLVDLTRQVLSKLANQVYLDAINAFRRKDVKALNIHSQKFIQLIKDIDVLLASDDNFLLGT WLESAKLLAENPSEMRQYEWNARTQVTMWFDTTPTNQSKLHDYANKFWSGLLEGYYLPRASSYFSYLSKSLEKNESFKLVEWRKQWVSFSNKWQAGLELY PVKAQGNFLTIAKALFD | |||
| Full Sequence |
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| Protein Sequence Length: 622 Download |
| MALQGINLPL AFSGQEAIWQ KVFMGFNISM EDLNDFFGGP AFLAWARMGN LHTWGGPLSK 60 NWLKQQLVLQ KKILSRMVEL GMTPVLPSFS GNVPAALKTI FPTANITRLG DWNTVDGDPH 120 WCCTYLLNPS DPLFVEIGEA FIKMQIKEYG DVTDIYNCDT FNENSPPTND TIYISSLGAA 180 VYKAMSNGDK DAVWLMQGWL FYSDSTFWKP PQMKALLHSV PVGKMIVLDL FADVKPIWAT 240 SSQFYGTPYV WCLLHNFGGN IEMYGTLDAI SSGPVDARIS KNSTMVGVGM CMEGIEQNPV 300 VYELMSEMAF RKEKVQVLEW LKTYTHRRYG KSVQQIKEAW AILYHTVYNC TDGIADHNID 360 FIVKFPDWDP SINFGSRPSK LNSMHTFRLR TRSRRFSFQE RSSDLPQAHL WYSTHEVVSA 420 LKLFLAAGND LAGSLTYRYD LVDLTRQVLS KLANQVYLDA INAFRRKDVK ALNIHSQKFI 480 QLIKDIDVLL ASDDNFLLGT WLESAKLLAE NPSEMRQYEW NARTQVTMWF DTTPTNQSKL 540 HDYANKFWSG LLEGYYLPRA SSYFSYLSKS LEKNESFKLV EWRKQWVSFS NKWQAGLELY 600 PVKAQGNFLT IAKALFDKYL S* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12972 | NAGLU_C | 6.0e-106 | 319 | 619 | 301 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| pfam05089 | NAGLU | 1.0e-158 | 1 | 314 | 314 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI24942.1 | 0 | 1 | 621 | 247 | 868 | unnamed protein product [Vitis vinifera] |
| GenBank | EEC75285.1 | 0 | 1 | 620 | 196 | 811 | hypothetical protein OsI_11626 [Oryza sativa Indica Group] |
| GenBank | EEE59081.1 | 0 | 1 | 621 | 196 | 812 | hypothetical protein OsJ_10898 [Oryza sativa Japonica Group] |
| RefSeq | XP_002273084.1 | 0 | 1 | 621 | 182 | 803 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314048.1 | 0 | 1 | 620 | 186 | 805 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 0 | 2 | 619 | 298 | 877 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vcb_A | 0 | 2 | 619 | 298 | 877 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vca_A | 0 | 2 | 619 | 298 | 877 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vc9_A | 0 | 2 | 619 | 298 | 877 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 0 | 2 | 619 | 321 | 900 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| HO783455 | 326 | 120 | 442 | 0 |
| HO783455 | 148 | 451 | 598 | 0 |
| CO085177 | 279 | 309 | 587 | 0 |
| CO131169 | 280 | 300 | 579 | 0 |
| HO783455 | 32 | 442 | 473 | 0.062 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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