| Basic Information | |
|---|---|
| Species | Gossypium raimondii |
| Cazyme ID | Gorai.004G207200.5 |
| Family | AA3 |
| Protein Properties | Length: 392 Molecular Weight: 42751 Isoelectric Point: 7.4434 |
| Chromosome | Chromosome/Scaffold: 04 Start: 53804667 End: 53809065 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 61 | 385 | 0 |
| LEYANPSGLTVFLHASVHKILFAIKGKRRPKAHGVVFRDATGAKHKAYLKQGSKNEIIISAGALGSPQLLMLSGVGPAQHLKSHDITVVLDQPLVGQGMS DNPMNAVFIPSPLPVEVSLIQVVGITHFGSYIEAASGENFAGGASSSPAVEYMNNLDETTFRGGFILEKVMGPISTGHLELRTRNPNDNPSVTFNYFKDP QDLQRCVQGIQTIEKIIESKAFFRFRYEFLSWPILLNMTANAPLNLLPKHYNPSMPLEVFCKDTVMTIWHYHGGCQVGKVVDLDYKVLGVDALRVIDGST FNDSPGTNPQATVMMLGRYMGVKIL | |||
| Full Sequence |
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| Protein Sequence Length: 392 Download |
| MEKSVAFEPS LGQWQSAVRD GLLEAGVMPS NGFTYDHIYG TKVGGTIFDQ QGNRHTAADL 60 LEYANPSGLT VFLHASVHKI LFAIKGKRRP KAHGVVFRDA TGAKHKAYLK QGSKNEIIIS 120 AGALGSPQLL MLSGVGPAQH LKSHDITVVL DQPLVGQGMS DNPMNAVFIP SPLPVEVSLI 180 QVVGITHFGS YIEAASGENF AGGASSSPAV EYMNNLDETT FRGGFILEKV MGPISTGHLE 240 LRTRNPNDNP SVTFNYFKDP QDLQRCVQGI QTIEKIIESK AFFRFRYEFL SWPILLNMTA 300 NAPLNLLPKH YNPSMPLEVF CKDTVMTIWH YHGGCQVGKV VDLDYKVLGV DALRVIDGST 360 FNDSPGTNPQ ATVMMLGRYM GVKILSERLA N* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR03970 | Rv0697 | 7.0e-23 | 57 | 377 | 343 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| pfam05199 | GMC_oxred_C | 1.0e-26 | 233 | 377 | 150 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR01810 | betA | 1.0e-27 | 22 | 377 | 390 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 3.0e-34 | 68 | 390 | 348 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 1 | 391 | 418 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI34759.1 | 0 | 1 | 391 | 158 | 574 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001053612.1 | 0 | 1 | 391 | 160 | 583 | Os04g0573100 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002282510.1 | 0 | 1 | 391 | 124 | 540 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002298074.1 | 0 | 1 | 390 | 157 | 571 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509694.1 | 0 | 1 | 390 | 161 | 543 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 1 | 391 | 141 | 520 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_A | 0 | 1 | 391 | 141 | 520 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdn_B | 0 | 1 | 391 | 141 | 520 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 1 | 391 | 141 | 520 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 1 | 391 | 141 | 520 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CO079313 | 277 | 81 | 357 | 0 |
| DT550126 | 265 | 88 | 352 | 0 |
| DT561858 | 267 | 1 | 267 | 0 |
| DT559444 | 263 | 86 | 348 | 0 |
| ES844522 | 247 | 21 | 266 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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