| Basic Information | |
|---|---|
| Species | Gossypium raimondii |
| Cazyme ID | Gorai.004G231200.1 |
| Family | GH29 |
| Protein Properties | Length: 521 Molecular Weight: 58296.8 Isoelectric Point: 5.8273 |
| Chromosome | Chromosome/Scaffold: 04 Start: 56832477 End: 56835708 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 47 | 345 | 0 |
| ASQLQWQLSSMALFLHFGPNTFTDSEWGTGHASPSVFNPTLLNASQWVHVAKEAGFSRVILTAKHHDGFCLWLSEYTDYSVKASPWRNGKGDVVAELAAG AKEAGIALGLYLSPWDRHESCYGKTLEYNEFYIGQMTELLTRYGDIKEVWLDGAKGEGEKDMEYYFDAWFSLIHQLQPDAVIFSDAGPDTRWIGDEAGVA GSTCWSLFNRSNAVIGGTNPQYSQGGDPHGHDWVPAECDVSIRPGWFWHASQVPKSALELLDIYYKSTGRNCLLLLNVPPNSSGLISDEDIQALQEFKE | |||
| Full Sequence |
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| Protein Sequence Length: 521 Download |
| MPNPSFNSRK PISVHALPIF VSLFFSAIPH SALKIPPPLP ILPLPSASQL QWQLSSMALF 60 LHFGPNTFTD SEWGTGHASP SVFNPTLLNA SQWVHVAKEA GFSRVILTAK HHDGFCLWLS 120 EYTDYSVKAS PWRNGKGDVV AELAAGAKEA GIALGLYLSP WDRHESCYGK TLEYNEFYIG 180 QMTELLTRYG DIKEVWLDGA KGEGEKDMEY YFDAWFSLIH QLQPDAVIFS DAGPDTRWIG 240 DEAGVAGSTC WSLFNRSNAV IGGTNPQYSQ GGDPHGHDWV PAECDVSIRP GWFWHASQVP 300 KSALELLDIY YKSTGRNCLL LLNVPPNSSG LISDEDIQAL QEFKELRRSI FSNNLAEKGL 360 LTASSIRGGN DNYQFSPYNV FEESIYTYWA PEEDQRDWVL YLDLQESVSF NVLQVQEPIH 420 MGQRIIKFHL EILSGGRWKN VISGTTVGYK RLLQFPTVQS RYLKLVIDMS RADPLISYMG 480 LHMDRFSILS HASNTTSQIY VNGSQVLRQV PNKDSQTATV * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00812 | Alpha_L_fucos | 1.0e-32 | 83 | 343 | 288 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| pfam01120 | Alpha_L_fucos | 1.0e-32 | 83 | 343 | 279 | + Alpha-L-fucosidase. | ||
| COG3669 | COG3669 | 4.0e-66 | 51 | 481 | 450 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_180377.2 | 0 | 36 | 501 | 29 | 493 | ATFUC1 (alpha-L-fucosidase 1); alpha-L-fucosidase [Arabidopsis thaliana] |
| Swiss-Prot | Q8GW72 | 0 | 36 | 501 | 29 | 493 | FUCO1_ARATH RecName: Full=Alpha-L-fucosidase 1; AltName: Full=Alpha-L-fucoside fucohydrolase; AltName: Full=Alpha-1,3/4-fucosidase; Short=AtFUC1; Flags: Precursor |
| RefSeq | XP_002276131.1 | 0 | 46 | 505 | 51 | 509 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313533.1 | 0 | 46 | 487 | 15 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523703.1 | 0 | 46 | 513 | 64 | 534 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ues_B | 0 | 45 | 477 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 45 | 477 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 45 | 477 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 45 | 477 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3uet_B | 0 | 45 | 477 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DY270181 | 324 | 10 | 333 | 0 |
| DY291901 | 282 | 49 | 330 | 0 |
| FC905625 | 316 | 10 | 325 | 0 |
| DY272403 | 338 | 7 | 343 | 0 |
| DY277939 | 319 | 7 | 325 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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