Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.005G075900.2 |
Family | GT47 |
Protein Properties | Length: 479 Molecular Weight: 53832.7 Isoelectric Point: 9.4555 |
Chromosome | Chromosome/Scaffold: 05 Start: 8662383 End: 8664846 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 54 | 403 | 0 |
QNSIKVYVANLPRSLNYGLLQQYWDSNHPDSRIPSDPDHQISTTHFSKPTRYPPYPENPLIKQYSAEYWIMGDLETPQGIRTASFAKRVFDVNEADVVFV PFFATLSAEMELGSGSGAFKKKAGNGDYLRQKKVLDFVRNTDAWKRSGGRDHVFVLTDPVAMWHFREEIAPAVLLVVDFGGWYRLDTKSSGGISSDTIRH TQVSLLKDVIVPYTHLLPRLQLSENQKRHTLLYFKGAKHRHRGGLVREKLWDLLVNEPGVIMEEGFPNATGREQSIKGMRSSEFCLHPAGDTPTSCRLFD AIQSLCIPVIVSDNVELPFEGMVDYSTFSVFVAVSDALRPNWLVSHLRSI |
Full Sequence |
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Protein Sequence Length: 479 Download |
MAIKGSTATK TAKSLFLTFT VLLSLSFFIF FFFFTSPVTE PTNSLPQTSF LSSQNSIKVY 60 VANLPRSLNY GLLQQYWDSN HPDSRIPSDP DHQISTTHFS KPTRYPPYPE NPLIKQYSAE 120 YWIMGDLETP QGIRTASFAK RVFDVNEADV VFVPFFATLS AEMELGSGSG AFKKKAGNGD 180 YLRQKKVLDF VRNTDAWKRS GGRDHVFVLT DPVAMWHFRE EIAPAVLLVV DFGGWYRLDT 240 KSSGGISSDT IRHTQVSLLK DVIVPYTHLL PRLQLSENQK RHTLLYFKGA KHRHRGGLVR 300 EKLWDLLVNE PGVIMEEGFP NATGREQSIK GMRSSEFCLH PAGDTPTSCR LFDAIQSLCI 360 PVIVSDNVEL PFEGMVDYST FSVFVAVSDA LRPNWLVSHL RSISEKLKNE FRQTMAKVQP 420 VFVYDNGHPD GIGPIPPDGA VNHIWRKVHQ KLPAIKEAIV RGKRKPANTS IPLRCHCT* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-57 | 53 | 403 | 363 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 42 | 477 | 42 | 476 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 1 | 478 | 1 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 14 | 478 | 17 | 476 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 23 | 478 | 1 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 46 | 478 | 44 | 478 | catalytic, putative [Ricinus communis] |