| Basic Information | |
|---|---|
| Species | Gossypium raimondii |
| Cazyme ID | Gorai.005G082700.3 |
| Family | GT47 |
| Protein Properties | Length: 347 Molecular Weight: 39452.4 Isoelectric Point: 9.9115 |
| Chromosome | Chromosome/Scaffold: 05 Start: 10128625 End: 10133146 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 79 | 332 | 2.8026e-45 |
| LSLKIYVYDENEIDGLKDLLYGRDGSISSNACLKGQWGSQVKIHRLLLESRFRTRKKEEADLFFVPAYVKCVRMLGGLNDKEINQTYVKVLSQMPYFRRS GGRDHIFVFPSGAGAHLFRSWATYINRSIILTPEGDRTDKKDTSAFNTWKDIIIPGNVDDGMMKTGATVFQPLPLSKRKYLANYLGRAQKKVGRLKLIEL AKQYPDKLECPELQFSGPNKLGRVEYFQHLGNSKFCLAPRGESSWTLRFYESFF | |||
| Full Sequence |
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| Protein Sequence Length: 347 Download |
| MSPKPRIFSA HSHTAPLCTR THQIAALILV TATFFFTRLF DQSFPPSPCY LDRHLNLHVA 60 KTNDAGHLLW PDRGYGSHLS LKIYVYDENE IDGLKDLLYG RDGSISSNAC LKGQWGSQVK 120 IHRLLLESRF RTRKKEEADL FFVPAYVKCV RMLGGLNDKE INQTYVKVLS QMPYFRRSGG 180 RDHIFVFPSG AGAHLFRSWA TYINRSIILT PEGDRTDKKD TSAFNTWKDI IIPGNVDDGM 240 MKTGATVFQP LPLSKRKYLA NYLGRAQKKV GRLKLIELAK QYPDKLECPE LQFSGPNKLG 300 RVEYFQHLGN SKFCLAPRGE SSWTLRFYES FFVVSLSFSN TCTQAF* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-29 | 81 | 332 | 264 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM61682.1 | 0 | 2 | 333 | 6 | 341 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_564141.1 | 0 | 2 | 333 | 6 | 341 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_973879.1 | 0 | 2 | 333 | 6 | 341 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002300942.1 | 0 | 6 | 333 | 10 | 339 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 6 | 333 | 10 | 339 | predicted protein [Populus trichocarpa] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DT562513 | 283 | 1 | 283 | 0 |
| CU531100 | 251 | 71 | 321 | 0 |
| BX841155 | 330 | 2 | 327 | 0 |
| HO781282 | 317 | 17 | 332 | 0 |
| DT560790 | 229 | 1 | 229 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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