| Basic Information | |
|---|---|
| Species | Gossypium raimondii |
| Cazyme ID | Gorai.005G082700.6 |
| Family | GT47 |
| Protein Properties | Length: 283 Molecular Weight: 32413.4 Isoelectric Point: 8.5549 |
| Chromosome | Chromosome/Scaffold: 05 Start: 10128625 End: 10133146 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 15 | 205 | 1.4e-37 |
| NHSGAGAHLFRSWATYINRSIILTPEGDRTDKKDTSAFNTWKDIIIPGNVDDGMMKTGATVFQPLPLSKRKYLANYLGRAQKKVGRLKLIELAKQYPDKL ECPELQFSGPNKLGRVEYFQHLGNSKFCLAPRGESSWTLRFYESFFVECVPVILSDQVELPFQNVIDYTEISIKWPSTSIGPELLDYLASI | |||
| Full Sequence |
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| Protein Sequence Length: 283 Download |
| MINFDSKVVC FLYVNHSGAG AHLFRSWATY INRSIILTPE GDRTDKKDTS AFNTWKDIII 60 PGNVDDGMMK TGATVFQPLP LSKRKYLANY LGRAQKKVGR LKLIELAKQY PDKLECPELQ 120 FSGPNKLGRV EYFQHLGNSK FCLAPRGESS WTLRFYESFF VECVPVILSD QVELPFQNVI 180 DYTEISIKWP STSIGPELLD YLASIPDEVI EQIIGRGRQV RCLWVYAPDS EPCSTMRALM 240 WELQRKVRQF HQSAETFWLH NGSVVNRNLV EFAKWKPPMP LP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-23 | 12 | 205 | 206 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002265632.1 | 0 | 12 | 282 | 189 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 12 | 282 | 190 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 12 | 282 | 190 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002458782.1 | 0 | 12 | 282 | 156 | 426 | hypothetical protein SORBIDRAFT_03g040220 [Sorghum bicolor] |
| RefSeq | XP_002526175.1 | 0 | 12 | 282 | 183 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| FE707913 | 272 | 12 | 283 | 0 |
| CX668832 | 248 | 12 | 259 | 0 |
| GR005989 | 246 | 17 | 262 | 0 |
| EL691051 | 248 | 37 | 283 | 0 |
| FY793499 | 241 | 43 | 283 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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