Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.005G266400.1 |
Family | GT47 |
Protein Properties | Length: 476 Molecular Weight: 54447.2 Isoelectric Point: 8.4095 |
Chromosome | Chromosome/Scaffold: 05 Start: 63928702 End: 63930761 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 84 | 423 | 0 |
VAVYVYNLPAEFNLGLLDDCSHLNVYTNMCPHVANHGLGQPLDNMDLQSSDSNPWFATHQFIAEMIFHARVDNHPCRTWDPSKANLFYVPFYGGLHVSSN FREPNHAIRDALAVRLVDFLQAQPTWRKNNGKDHFLALGRTSWDFMRTNSGPDFGANCLLNLPCVKNMSVLTVERNPWKGSNQHGIPYPSYFHPSTSDQM MTWQNMMRQSNRPYLFSFIGAPRKGVGKAAIRDEMIKQCMESTQCKILKCDHGNPKCYNPSEILKVMRESRFCLQAPGDSFTRRSTFDAILSGCIPVFFS RHTAYTQYSWFLPEEASKYSVYMDEQSEESKRIEEVLMKI |
Full Sequence |
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Protein Sequence Length: 476 Download |
MLLSKKQPSA AATQWIEKVK YHKNRDSYFK FLGNPHFRYT AFLLVFLSLW FLLQVFWFPP 60 TKPTQTKFST TTPKPSAGKC NGDVAVYVYN LPAEFNLGLL DDCSHLNVYT NMCPHVANHG 120 LGQPLDNMDL QSSDSNPWFA THQFIAEMIF HARVDNHPCR TWDPSKANLF YVPFYGGLHV 180 SSNFREPNHA IRDALAVRLV DFLQAQPTWR KNNGKDHFLA LGRTSWDFMR TNSGPDFGAN 240 CLLNLPCVKN MSVLTVERNP WKGSNQHGIP YPSYFHPSTS DQMMTWQNMM RQSNRPYLFS 300 FIGAPRKGVG KAAIRDEMIK QCMESTQCKI LKCDHGNPKC YNPSEILKVM RESRFCLQAP 360 GDSFTRRSTF DAILSGCIPV FFSRHTAYTQ YSWFLPEEAS KYSVYMDEQS EESKRIEEVL 420 MKIPKEEVDT MRATVIDMIP RLTYAHPNAS HSDLGFEDAV DVALQALAQH VRDKV* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-68 | 86 | 423 | 352 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42883.1 | 0 | 17 | 475 | 20 | 451 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_177014.1 | 0 | 17 | 475 | 20 | 451 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270383.1 | 0 | 82 | 475 | 121 | 503 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300452.1 | 0 | 80 | 467 | 1 | 391 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336132.1 | 0 | 67 | 467 | 9 | 412 | predicted protein [Populus trichocarpa] |