Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.009G027500.2 |
Family | GT21 |
Protein Properties | Length: 388 Molecular Weight: 43243.6 Isoelectric Point: 6.4523 |
Chromosome | Chromosome/Scaffold: 09 Start: 2087486 End: 2091915 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT21 | 84 | 273 | 8.4e-34 |
PRVSVVMPLKGFGEHNLHNWKSQITSLYGGPIEFLFVVESTEDPAYHAVSQLITEFKGDVDARVIVAGLSTTCSQKIHNQLVGVENMHKDSKYVLFLDDD VRFHPGSIGVLTTEMEKNPEIFIQTGYPLDLPSGTLGSYCIYEYHMPCSMGFATGGKTFFLWGGCMMMHADDFRHDNYGVVSGLRDGGYS |
Full Sequence |
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Protein Sequence Length: 388 Download |
MSALHSADSF LLSLSRAFCS PLAVFIQIQG CVICLTLAIG WAFAAYVRKR EINRIEDGIK 60 GGNSFAFLCH DIYELEHSNQ VNLPRVSVVM PLKGFGEHNL HNWKSQITSL YGGPIEFLFV 120 VESTEDPAYH AVSQLITEFK GDVDARVIVA GLSTTCSQKI HNQLVGVENM HKDSKYVLFL 180 DDDVRFHPGS IGVLTTEMEK NPEIFIQTGY PLDLPSGTLG SYCIYEYHMP CSMGFATGGK 240 TFFLWGGCMM MHADDFRHDN YGVVSGLRDG GYSDDMTLAA IAGAHKRLIT SPPVAVFPHP 300 IASDLTFSRY WNYLRKQTFV LESYISTVNW LMNRALFLTH FYLSWGFVAP YFMAMVHVAA 360 ALQIYIKGYS YGETTCTSGG EHTLFPF* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR03472 | HpnI | 0.0002 | 84 | 200 | 119 | + hopanoid biosynthesis associated glycosyl transferase protein HpnI. This family of genes include a glycosyl transferase, group 2 domain (pfam00535) which are responsible, generally for the transfer of nucleotide-diphosphate sugars to substrates such as polysaccharides and lipids. The member of this clade from Acidithiobacillus ferrooxidans ATCC 23270 (AFE_0974) is found in the same locus as squalene-hopene cyclase (SHC, TIGR01507) and other genes associated with the biosynthesis of hopanoid natural products. Similarly, in Ralstonia eutropha JMP134 (Reut_B4902) this gene is adjacent to HpnAB, IspH and HpnH (TIGR03470), although SHC itself is elsewhere in the genome. Notably, this gene (here named HpnI) and three others form a conserved set (HpnIJKL) which occur in a subset of all genomes containing the SHC enzyme. This relationship was discerned using the method of partial phylogenetic profiling. This group includes Zymomonas mobilis, the organism where the initial hopanoid biosynthesis locus was described consisting of the genes HpnA-E and SHC (HpnF). Continuing past SHC are found a phosphorylase enzyme (ZMO0873, i.e. HpnG, TIGR03468) and another radical SAM enzyme (ZMO0874), HpnH. Although discontinuous in Z. mobilis, we continue the gene symbol sequence with HpnIJKL. Hopanoids are known to feature polar glycosyl head groups in many organisms. | ||
pfam13641 | Glyco_tranf_2_3 | 7.0e-6 | 84 | 257 | 181 | + Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis. | ||
COG1215 | COG1215 | 2.0e-8 | 79 | 368 | 307 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
cd02520 | Glucosylceramide_synthase | 3.0e-9 | 84 | 204 | 124 | + Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis. UDP-glucose:N-acylsphingosine D-glucosyltransferase (glucosylceramide synthase or ceramide glucosyltransferase) catalyzes the first glycosylation step of glycosphingolipid synthesis. Its product, glucosylceramide, serves as the core of more than 300 glycosphingolipids (GSL). GSLs are a group of membrane components that have the lipid portion embedded in the outer plasma membrane leaflet and the sugar chains extended to the outer environment. Several lines of evidence suggest the importance of GSLs in various cellular processes such as differentiation, adhesion, proliferation, and cell-cell recognition. In pathogenic fungus Cryptococcus neoformans, glucosylceramide serves as an antigen that elicits an antibody response in patients and it is essential for fungal growth in host extracellular environment. | ||
pfam13506 | Glyco_transf_21 | 4.0e-10 | 143 | 315 | 177 | + Glycosyl transferase family 21. This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAK73021.1 | 0 | 2 | 380 | 3 | 381 | AF367245_1 ceramide glucosyltransferase [Gossypium arboreum] |
GenBank | AAL11579.1 | 0 | 1 | 380 | 1 | 380 | AF424585_1 At2g19880/F6F22.9 [Arabidopsis thaliana] |
GenBank | ABK95617.1 | 0 | 5 | 380 | 3 | 378 | unknown [Populus trichocarpa] |
RefSeq | XP_002329645.1 | 0 | 1 | 380 | 1 | 387 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514215.1 | 0 | 2 | 380 | 5 | 383 | ceramide glucosyltransferase, putative [Ricinus communis] |