| Basic Information | |
|---|---|
| Species | Gossypium raimondii |
| Cazyme ID | Gorai.009G159000.1 |
| Family | GT20 |
| Protein Properties | Length: 962 Molecular Weight: 108940 Isoelectric Point: 6.7141 |
| Chromosome | Chromosome/Scaffold: 09 Start: 12179234 End: 12185399 |
| Description | trehalose-6-phosphate synthase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 108 | 579 | 0 |
| SRTSRERLLVVANRLPVSAVRRGVDSWHLEISVGGLVSALLGVKEFETRWIGWAGVNVPDEIGQRALIKALAEKRCIPVFLDEEIVHQYYNGYCNNILWP LFHYLGLPQEDRLATTRSFQSQFDAYKKANQMFAEVVKEHYVEGDVVWCHDYHLMFLPKCLKERNRKMKVGWFLHTPFPSSEIHRTLPSRSELLRSVLAA DLVGFHTYDYARHFVSACTRILGLEGTPEGVEDQGRLTRVAAFPIGIDSDRFIRALELPQVQDHMKELKERFAGRKVMLGVDRLDMIKGIPQKILAFEKF LEENPNWRDKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDVALVTSLRDGMNLVSYEFVACQASKKG VLILSEFAGAAQSLGAGAILVNPWNVTEVASSIGYALNMPADEREKRHHHNFVHVTTHTSQEWAATFVSELN | |||
| Full Sequence |
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| Protein Sequence Length: 962 Download |
| MSISSPDTCI SHNNNNLPNL SNKSNGMRGN KYNCNNSGTP RTRLERLLRE RELRKFNKSL 60 NDGETELSNN DSFSPDSFEA FSWFNDEESL ETISANGCST DGCERQDSRT SRERLLVVAN 120 RLPVSAVRRG VDSWHLEISV GGLVSALLGV KEFETRWIGW AGVNVPDEIG QRALIKALAE 180 KRCIPVFLDE EIVHQYYNGY CNNILWPLFH YLGLPQEDRL ATTRSFQSQF DAYKKANQMF 240 AEVVKEHYVE GDVVWCHDYH LMFLPKCLKE RNRKMKVGWF LHTPFPSSEI HRTLPSRSEL 300 LRSVLAADLV GFHTYDYARH FVSACTRILG LEGTPEGVED QGRLTRVAAF PIGIDSDRFI 360 RALELPQVQD HMKELKERFA GRKVMLGVDR LDMIKGIPQK ILAFEKFLEE NPNWRDKVVL 420 LQIAVPTRTD VPEYQKLTSQ VHEIVGRING RFGTLTAVPI HHLDRSLDFH ALCALYAVTD 480 VALVTSLRDG MNLVSYEFVA CQASKKGVLI LSEFAGAAQS LGAGAILVNP WNVTEVASSI 540 GYALNMPADE REKRHHHNFV HVTTHTSQEW AATFVSELND TIVEAQLRTR QIPPPLPIEV 600 AVDRYAKSNN RLLILGFNAT LTEPVDTLGR KGSQIKEMEP KLRPDLQEPL RKLCDDPKTT 660 IVVLSGSDRS VLDDNFGDYS MWLAAENGMF LRATKGDWMT TMPENLNMEW VDSVKHVFEY 720 FTERTPRSHF ELRETSLIWN YKYADVEFGR LQARDLLQHL WTGPISNASL DVVQGSRSIE 780 VRSVGVTKGA AIDRILGEIV HNKGMKEPID YVLCIGHFLA KDEDIYTFFE PELPSEVPAP 840 VRSHVTPPVR TSVSKLSTSR SLSREDRLKK HRPMPTIERS KSYHVNTDVF QSRVVDRMSL 900 QEGSSVLDLQ GDNYFSCSVA RKRSNARYLL RSSDDVVKLL TELTNSWIDS MNTDGSTMEG 960 N* 1020 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03064 | PLN03064 | 0 | 27 | 946 | 933 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03063 | PLN03063 | 0 | 107 | 943 | 837 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PRK14501 | PRK14501 | 0 | 114 | 816 | 712 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| TIGR02400 | trehalose_OtsA | 0 | 114 | 580 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
| pfam00982 | Glyco_transf_20 | 0 | 113 | 580 | 474 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAA69879.1 | 0 | 27 | 946 | 1 | 938 | trehalose-6-phosphate synthase [Arabidopsis thaliana] |
| RefSeq | NP_177979.1 | 0 | 27 | 946 | 1 | 938 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002305707.1 | 0 | 48 | 946 | 1 | 895 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002331300.1 | 0 | 27 | 946 | 1 | 920 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002522296.1 | 0 | 39 | 946 | 10 | 911 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1uqu_B | 0 | 114 | 590 | 3 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| PDB | 1uqu_A | 0 | 114 | 590 | 3 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| PDB | 1uqt_B | 0 | 114 | 590 | 3 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| PDB | 1uqt_A | 0 | 114 | 590 | 3 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| PDB | 2wtx_D | 0 | 114 | 590 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX546763 | 304 | 101 | 403 | 0 |
| DW069910 | 288 | 200 | 487 | 0 |
| CV711307 | 294 | 111 | 404 | 0 |
| ES813375 | 361 | 475 | 835 | 0 |
| CB651133 | 280 | 141 | 420 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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