Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.009G307300.1 |
Family | GT64 |
Protein Properties | Length: 784 Molecular Weight: 88818.8 Isoelectric Point: 8.5105 |
Chromosome | Chromosome/Scaffold: 09 Start: 28073388 End: 28079655 |
Description | glycosyltransferase family protein 47 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT64 | 537 | 772 | 0 |
FTLLTMTYDARLWNLKMFVNHYSRCASVKEILVVWNKGIPPKVSDLNSAVPVRIRVEDLNSLNNRFKVDPLIKTRAVLELDDDIMMPCDDVERGFMLWRQ HPDRIVGFYPRYVDGSRLEYSGEKYARKNKGYNMILTGAAFMDSQVAFERYWSEQAKPGREVVDKYFNCEDVLMNFLYANASSSKTVEYVRPAWAIDTSK LSSAAISRDTNVHYKIRSECLRKFSDMYGSMSGRRW |
Full Sequence |
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Protein Sequence Length: 784 Download |
MVVAGGGDNG GGGGNCCMKW WQHNRNHYYH QHHYNHNSNS SGNSNSASGG GGGGGRMVAA 60 GFVFCLVCFV INGLIAVLYG WLILTPPVSL NERKGLPWLG CQEDNEGSWA IGVFFGQSPF 120 SLKPIETTEI WRNESAAWPV ANPVITCASA SDSGFPSNFV ADPFLYVQGD VFYLFYETKN 180 SFTMQGDIGV AKSIDKGATW QQLGIALDEE WHLSYPYVFN YLGQVYMMPE SSQKGELRLY 240 RVTNFPLEWE LDRVIMKKPL IDSFIIDHNG EYWLFGSEHN SFGTTNGRLE IWYSNSPLGP 300 WKPHKKNPIY NTYRNFGARN GGRPFRYNGN LYRIGQDCGE TYGRRVRIFK VEVLSRVDYK 360 EVEVPFPFEE SSKGRNAWNG ARYHHLDVQQ LKSGEWVGVM DGDRVPSGDS VHRFLLGCAS 420 VAAVSGLILF LGVLLGAVNC IIPLNWCADY SGKRSDTLIA WERANVFSSK LRRVFSRLNR 480 VPSFLRSWIK PNTFAGRSVL TLIFALGVVL SCTGVTFIYG GSGAEEPYSW KGQFSQFTLL 540 TMTYDARLWN LKMFVNHYSR CASVKEILVV WNKGIPPKVS DLNSAVPVRI RVEDLNSLNN 600 RFKVDPLIKT RAVLELDDDI MMPCDDVERG FMLWRQHPDR IVGFYPRYVD GSRLEYSGEK 660 YARKNKGYNM ILTGAAFMDS QVAFERYWSE QAKPGREVVD KYFNCEDVLM NFLYANASSS 720 KTVEYVRPAW AIDTSKLSSA AISRDTNVHY KIRSECLRKF SDMYGSMSGR RWEFDSRKDR 780 WDV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd08994 | GH43_like_2 | 0.003 | 263 | 348 | 89 | + Glycosyl hydrolase 43-like family consists of hypothetical proteins. This subfamily mostly contains uncharacterized proteins similar to glycosyl hydrolase family 43 (GH43) which includes enzymes with beta-xylosidase (EC 3.2.1.37) and alpha-L-arabinofuranosidase (EC 3.2.1.55) and possibly bifunctional xylosidase/arabinofuranosidase activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the enzymes in this family display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
cd08978 | GH_F | 0.001 | 131 | 348 | 238 | + Glycosyl hydrolase families 43 and 62 form CAZY clan GH-F. This glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) includes family 43 (GH43) and 62 (GH62). GH43 includes enzymes with beta-xylosidase (EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanases (beta-xylanases) and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. GH62 includes enzymes characterized as arabinofuranosidases (alpha-L-arabinofuranosidases; EC 3.2.1.55) that specifically cleave either alpha-1,2 or alpha-1,3-L-arabinofuranose side chains from xylans. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the enzymes in this family display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. GH62 are also predicted to be inverting enzymes. A common structural feature of both, GH43 and GH62 enzymes, is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
pfam09258 | Glyco_transf_64 | 3.0e-71 | 537 | 776 | 247 | + Glycosyl transferase family 64 domain. Members of this family catalyze the transfer reaction of N-acetylglucosamine and N-acetylgalactosamine from the respective UDP-sugars to the non-reducing end of [glucuronic acid]beta 1-3[galactose]beta 1-O-naphthalenemethanol, an acceptor substrate analog of the natural common linker of various glycosylaminoglycans. They are also required for the biosynthesis of heparan-sulphate. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005975 | carbohydrate metabolic process |
GO:0016758 | transferase activity, transferring hexosyl groups |
GO:0031227 | intrinsic to endoplasmic reticulum membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAB85556.1 | 0 | 30 | 783 | 24 | 764 | putative protein [Arabidopsis thaliana] |
RefSeq | NP_196070.2 | 0 | 30 | 783 | 25 | 765 | glycosyltransferase family protein 47 [Arabidopsis thaliana] |
RefSeq | XP_002262646.1 | 0 | 96 | 782 | 68 | 755 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002315348.1 | 0 | 169 | 783 | 232 | 847 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002532924.1 | 0 | 95 | 783 | 15 | 704 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1on8_B | 9e-27 | 531 | 767 | 24 | 270 | A Chain A, Human Beta 1,3-Glucuronyltransferase I (Glcat-I) In Complex With Udp And Gal-Gal(6-So4)-Xyl(2-Po4)-O-Ser |
PDB | 1on8_A | 9e-27 | 531 | 767 | 24 | 270 | A Chain A, Human Beta 1,3-Glucuronyltransferase I (Glcat-I) In Complex With Udp And Gal-Gal(6-So4)-Xyl(2-Po4)-O-Ser |
PDB | 1on6_B | 9e-27 | 531 | 767 | 24 | 270 | A Chain A, Human Beta 1,3-Glucuronyltransferase I (Glcat-I) In Complex With Udp And Gal-Gal(6-So4)-Xyl(2-Po4)-O-Ser |
PDB | 1on6_A | 9e-27 | 531 | 767 | 24 | 270 | A Chain A, Human Beta 1,3-Glucuronyltransferase I (Glcat-I) In Complex With Udp And Gal-Gal(6-So4)-Xyl(2-Po4)-O-Ser |
PDB | 1omz_B | 9e-27 | 531 | 767 | 24 | 270 | A Chain A, Human Beta 1,3-Glucuronyltransferase I (Glcat-I) In Complex With Udp And Gal-Gal(6-So4)-Xyl(2-Po4)-O-Ser |