Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.010G048500.1 |
Family | GT51 |
Protein Properties | Length: 1326 Molecular Weight: 147838 Isoelectric Point: 7.9398 |
Chromosome | Chromosome/Scaffold: 10 Start: 5299130 End: 5311758 |
Description | S-locus lectin protein kinase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT51 | 1128 | 1237 | 4.6e-38 |
LNEKLVKNTFLKNERTFWRKILEMVLALALERTMSKQRILSSYVCKIYWGHGINGIESASNFYFGKHPSQLSLAESAMLAGLIPAPEHRSPLRDRSSGKT FQARVLKRMV |
Full Sequence |
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Protein Sequence Length: 1326 Download |
MSLAVASPHR SMIHCKTSKF RFKNPQNLFG RTLTFYSLKS PTHFNSLLCL RVHSVRPESP 60 SIQTHHPIQE LLPLLAFSLS LLCFRLLSNV LLPDFALRWQ SLVAFSREAE ARTKSYPKHL 120 WQAIVAYEDR RFFTHFGIDP VGIGRAVLSL SARGGGSTIT QQVGKVYLVH GNTYLIIIDK 180 HLARLPSLRS LLILFSISME SFLFFIFGFL FYSSVSAKSF SEFIYPNFSA SHFSFIDKDG 240 AFLFSRNGTF KASIYNPEAQ TNFYLCIIHV ESNTIIWSAN RDSPISSSGK MDLTVNGISI 300 ADPDGNPKWS TPQLRTTIYA LLLTEMGNLV LLDKFNGSLW ESFYHPTDTI VIGQQLPVGA 360 KLSNAVSESN LSTGDYRFMV SASDALLQWH GQTYWILSMD TKAYVNSNYV VEYMEMNKTG 420 LSLFGHNGSV VVIQLNLAPA TFRLAKLDVL GHFTVNSFSG GKWVQEFVGP IDDCQIPASC 480 GKLGLCTGDS TSKAPTCSCP SDFHPASQNI GGCLPSGSSY SLPTACDSTN NVNESNSSTV 540 SYLRLGSGID YFSLLFSQPV RYGVRFPVCQ DLCSEDCACL GMFYENSSGS CYVLENDLGS 600 VILSSTVEND FLGYVKVLVG PISTDSGGDN SFSNEKNEFP IAAIVLLPSI GFFLLAALVF 660 FWWKRRLRSK GGEIKLGHLN SGSSEDMDAF YIPGLPQKFD YEELEAATDN FKTQIGSGGF 720 GSVYRGTLPD KTVVAVKKIS NPGIQGKKEF CTEIAVIGNI HHVNLVKLRG FCAQGRQRFL 780 VYEYMNRGSL DRTLFGSGAV LEWQERFDIA LGTARGLAYL HRGCEHKIIH CDVKPENILL 840 HDHFQAKISD FGLSKLLTPE QSSLFTTMRG TRGYLAPEWL TNSAISEKTD VYSFGMVLLE 900 LVSGRKNCSL KSQSHSIEDT NSGGGNSLSS SVMGLIYFPL LALEMHEQGR YLELADAKLE 960 GRVTNKEVEK LVRVALCCVH EEPALRPSMA TVVGMLEGGL PLGQPRVESL NFLRFYGRRF 1020 TEASMIEEER RQSDFMLFPQ ANVSHSSTTG SNACLSYISS QQISVSSLNF VMQLYIFLWY 1080 RWDNLWLWLE YGSAVLTTFS SNSLVIFFLA YFKLVVQTWP GGTSSFLLNE KLVKNTFLKN 1140 ERTFWRKILE MVLALALERT MSKQRILSSY VCKIYWGHGI NGIESASNFY FGKHPSQLSL 1200 AESAMLAGLI PAPEHRSPLR DRSSGKTFQA RVLKRMVKSG FLDIKMALLT VRQPLYVRLR 1260 RPEHADELSD ASSFSELGVG VKSNVNEEGT ESTLKGTWDW ERESKIREVC EEMERWAIKA 1320 QLRSS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
smart00221 | STYKc | 2.0e-46 | 711 | 996 | 305 | + Protein kinase; unclassified specificity. Phosphotransferases. The specificity of this class of kinases can not be predicted. Possible dual-specificity Ser/Thr/Tyr kinase. | ||
smart00219 | TyrKc | 4.0e-47 | 711 | 996 | 303 | + Tyrosine kinase, catalytic domain. Phosphotransferases. Tyrosine-specific kinase subfamily. | ||
smart00220 | S_TKc | 3.0e-48 | 714 | 905 | 194 | + Serine/Threonine protein kinases, catalytic domain. Phosphotransferases. Serine or threonine-specific kinase subfamily. | ||
pfam00069 | Pkinase | 6.0e-51 | 714 | 905 | 196 | + Protein kinase domain. | ||
cd00180 | PKc | 1.0e-51 | 715 | 901 | 191 | + Catalytic domain of Protein Kinases. Protein Kinases (PKs), catalytic (c) domain. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase. PKs make up a large family of serine/threonine kinases, protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation, about 95%, occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and 550 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0004672 | protein kinase activity |
GO:0005524 | ATP binding |
GO:0005529 | Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates." [CHEBI:16646, GOC:mah] |
GO:0006468 | protein phosphorylation |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN72729.1 | 0 | 48 | 1026 | 55 | 953 | hypothetical protein [Vitis vinifera] |
EMBL | CAN72729.1 | 5e-40 | 1174 | 1319 | 953 | 1098 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_198387.2 | 0 | 215 | 1064 | 21 | 869 | ATP binding / carbohydrate binding / kinase/ protein kinase/ protein serine/threonine kinase/ protein tyrosine kinase/ sugar binding [Arabidopsis thaliana] |
RefSeq | XP_002284416.1 | 0 | 48 | 1064 | 55 | 1046 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002513778.1 | 0 | 268 | 1064 | 1 | 790 | s-receptor kinase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3ulz_A | 0 | 694 | 998 | 15 | 308 | A Chain A, Crystal Structure Of The R3 Form Of Pectate Lyase A, Erwinia Chrysanthemi |
PDB | 3uim_A | 0 | 694 | 998 | 15 | 308 | A Chain A, Structural Basis For The Impact Of Phosphorylation On Plant Receptor- Like Kinase Bak1 Activation |
PDB | 3tl8_H | 0 | 694 | 998 | 23 | 316 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
PDB | 3tl8_G | 0 | 694 | 998 | 23 | 316 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
PDB | 3tl8_D | 0 | 694 | 998 | 23 | 316 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
Transmembrane Domains | ||||
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Start | End | |||
191 | 213 | |||
641 | 663 |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DV131627 | 216 | 743 | 956 | 0 |
DN498533 | 185 | 726 | 910 | 0 |
BQ629746 | 196 | 725 | 920 | 0 |
BQ623780 | 204 | 774 | 977 | 0 |
EE172103 | 211 | 693 | 902 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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