| Basic Information | |
|---|---|
| Species | Gossypium raimondii |
| Cazyme ID | Gorai.011G003500.2 |
| Family | GH47 |
| Protein Properties | Length: 556 Molecular Weight: 62858.3 Isoelectric Point: 5.9988 |
| Chromosome | Chromosome/Scaffold: 11 Start: 286791 End: 296648 |
| Description | alpha-mannosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH47 | 94 | 524 | 0 |
| AMIHAWSAYEKYAWGNDELLPQTQSGENSFGGLGATIIDSLDTLLIMGLDEQFQKAREWVANTLDFNKTYDASVFETTIRVVGGLLSTYDLSGDNIFLEK ARDIADRLLPAWDTPSGIPYNIIDLAHGNAHNPGWTGGDSILADSGTEQLEFIALSQRTGDPKYQEKVEKAIVALNKTFPADGLVPIYVNPNDGTAYGTI TFGAMGDSFYEYLLKAWIQGNKTSSVKPYRDMWETSMKGLVSLIRRSSPSSFAYICEKTRETLTDKMDELACFAPGMLALGSSGYGKVEAKKILSLAEEL AWTCYNFYQSTHTKLSGENYLFNPGRDMSVGTTWNILRPETVESLFYLWRLTGNVTYQEWGWNIFQAFEKNCRIESGYVGLTDVNLALKDNKMQTFFLAE TLKYLYLLFSPPTVIPLDEWVFNTEAHPLRI | |||
| Full Sequence |
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| Protein Sequence Length: 556 Download |
| MARIRSSSSS SKFRYCNPSY YLKRPKRLAL LLILFVSASS FVWDRQTLVR EHEFEVSKLN 60 DEVRRLQNML EEFTNRVPAN VPIEMQRREK VKEAMIHAWS AYEKYAWGND ELLPQTQSGE 120 NSFGGLGATI IDSLDTLLIM GLDEQFQKAR EWVANTLDFN KTYDASVFET TIRVVGGLLS 180 TYDLSGDNIF LEKARDIADR LLPAWDTPSG IPYNIIDLAH GNAHNPGWTG GDSILADSGT 240 EQLEFIALSQ RTGDPKYQEK VEKAIVALNK TFPADGLVPI YVNPNDGTAY GTITFGAMGD 300 SFYEYLLKAW IQGNKTSSVK PYRDMWETSM KGLVSLIRRS SPSSFAYICE KTRETLTDKM 360 DELACFAPGM LALGSSGYGK VEAKKILSLA EELAWTCYNF YQSTHTKLSG ENYLFNPGRD 420 MSVGTTWNIL RPETVESLFY LWRLTGNVTY QEWGWNIFQA FEKNCRIESG YVGLTDVNLA 480 LKDNKMQTFF LAETLKYLYL LFSPPTVIPL DEWVFNTEAH PLRIVNRNDN IAGSERQHKP 540 TVGLQGRKTG RFGGN* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG3116 | FtsL | 0.008 | 28 | 96 | 81 | + Cell division protein [Cell division and chromosome partitioning] | ||
| COG1331 | COG1331 | 0.008 | 173 | 268 | 97 | + Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones] | ||
| TIGR03897 | lanti_2_LanM | 0.002 | 174 | 265 | 101 | + type 2 lantibiotic biosynthesis protein LanM. Members of this family are known generally as LanM, a multifunctional enzyme of lantibiotic biosynthesis. This catalysis by LanM distinguishes the type 2 lantibiotics, such as mersacidin, cinnamycin, and lichenicidin, from LanBC-produced type 1 lantibiotics such as nisin and subtilin. The N-terminal domain contains regions associated with Ser and Thr dehydration. The C-terminal region contains a pfam05147 domain, which catalyzes the formation of the lanthionine bridge [Cellular processes, Toxin production and resistance]. | ||
| pfam01532 | Glyco_hydro_47 | 0 | 94 | 524 | 451 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| PTZ00470 | PTZ00470 | 0 | 87 | 528 | 454 | + glycoside hydrolase family 47 protein; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAK92711.1 | 0 | 1 | 552 | 1 | 569 | putative mannosidase [Arabidopsis thaliana] |
| EMBL | CBI18472.1 | 0 | 1 | 551 | 1 | 571 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_175570.1 | 0 | 1 | 551 | 1 | 556 | mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Arabidopsis thaliana] |
| RefSeq | NP_566675.1 | 0 | 1 | 552 | 1 | 569 | mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002310939.1 | 0 | 1 | 511 | 1 | 524 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 0 | 75 | 536 | 9 | 478 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 0 | 79 | 524 | 1 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 82 | 524 | 4 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 82 | 524 | 4 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 81 | 524 | 81 | 534 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| HO780776 | 515 | 20 | 491 | 0 |
| CU615093 | 325 | 234 | 556 | 0 |
| DY974119 | 307 | 155 | 460 | 0 |
| GO877285 | 307 | 142 | 447 | 0 |
| HO780776 | 76 | 482 | 555 | 1e-18 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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